Ugu Weyn Ee >> Daroogada Vs. Saaxiib >> Phenylephrine iyo pseudoephedrine: Kala duwanaanshaha, isku ekaanshaha, iyo yaa adiga kuu fiican

Phenylephrine iyo pseudoephedrine: Kala duwanaanshaha, isku ekaanshaha, iyo yaa adiga kuu fiican

Daroogada Vs. Saaxiib

Waxaa jira arrimo fara badan oo wax ku biiriya ciriiriga sanka iyo cadaadiska sanka, gaar ahaan xasaasiyadda xilliyeed ee xilli xasaasiga iyo hargabka caadiga ah. Cadaadiska sanka iyo sanka ayaa wax u dhimi kara neefsashada sanka, waxay u horseedi karaan madax xanuun, waxayna yareyn karaan wax soo saarka. Phenylephrine (Sudafed PE) iyo pseudoephedrine (Sudafed) waa laba nooc oo sun-yareyaal ah oo waxtar u yeelan kara yareynta cadaadiska sanka. Daawooyinkani waxay ku shaqeeyaan iyagoo si toos ah u kicin kara soo-dhoweynta adrenergic ee marinka sanka, iyo sidoo kale qaybaha kale ee jirka. In kasta oo ay siyaabo kala mid yihiin, haddana waxaa jira kala duwanaansho fure u ah oo go'aamin kara midka adiga saxda kuu ah.

Maxay yihiin farqiga ugu weyn ee u dhexeeya phenylephrine iyo pseudoephedrine?

Phenylephrine (Waa maxay Phenylephrine?) Waa sanka sanka ka suuxaa oo la heli karo kaligiis ama waxyaabo kala duwan oo isugu jira hargab iyo hargab. Waxaa laga heli karaa miiska laga iibsado (OTC), umana baahna rijeeto ama qoritaan macluumaad iibsi. Phenylephrine waa awood leh alfa-adrenergic agonist wuxuuna leeyahay waxqabad beta-adrenergic agonist ah. Daawooyinka loo yaqaan 'Alpha-adrenergic receptors', markii la kiciyo, ayaa mas'uul ka ah ciriiriga xididdada dhiigga. Daawooyinka Beta-adrenergic, marka la kiciyo, waxay mas'uul ka yihiin nasashada xididdada dhiigga, waxayna sidoo kale keenaan kororka garaaca wadnaha. In kasta oo ay keento xoogaa vasoconstriction ah marinka sanka kaas oo yareyn kara cadaadiska sanka, wuxuu kaloo keenaa vasoconstriction jirka oo dhan kaasoo kordhin kara cadaadiska dhiigga. Phenylephrine waxaa lagu heli karaa diyaargarowga afka sida kaniiniga ama dareeraha, iyo sidoo kale xalka la isku duro. Xalka la isku duro ayaa kaliya lagu maamuli doonaa goobta daryeelka caafimaadka.

Pseudoephedrine (Waa maxay Pseudoephedrine?) Waa sanka suuxdinta oo sidoo kale iskiis loo heli karo ama noocyo kala duwan oo isugu jira hargab iyo hargab. Waa la heli karaa iyada oo aan dhakhtar qorin, laakiin iibsashadiisu waa ku xaddidan tahay heerar kala duwan. Gobol kasta, oo ay weheliso tilmaamaha federaalka, ayaa go'aamiya xadka iibsiga macaamiisheeda. Iibsashada 'pseudoephedrine' waa inay ka dhacdaa miiska farmashiyaha iyadoo farmashiistaha uu joogo isla markaana lagu qoro keydka macluumaadka. Xayiraadahani hada way jiraan maxaa yeelay pseudoephedrine waa qayb muhiim u ah soo saarida sharci darada ah ee methamphetamine.

Pseudoephedrine waxay kicisaa xayawaanka alfa-adrenergic ee sanka sanka, iyo sidoo kale beta-adrenergic receptors jirka oo dhan. Tani waxay u horseedaa sanka oo suux noqda iyo nasashada neefta, laakiin sidoo kale waxay u horseedaa garaaca wadnaha oo kordha iyo foosha. Waxaa lagu heli karaa diyaargarowga afka sida kiniin ama dareere, iyo sidoo kale xalka la isku duro. Xalka la isku duro ayaa kaliya lagu maamuli doonaa goobta daryeelka caafimaadka.

Farqiga ugu weyn ee u dhexeeya phenylephrine iyo pseudoephedrine
	Phenylephrine	Pseudoephedrine
Fasalka daroogada	Cudurka Alpha-adrenergic	Alpha-adrenergic iyo beta-adrenergic agonist
Summad / astaan guud	Sumadda la heli karo iyo mid guud	Sumadda la heli karo iyo mid guud
Waa maxay magaca sumaddu?	Sudafed PE	Sudafed
Waa noocee (yada) daroogadu soo gasho?	Kiniin si dhakhso leh loo sii daayo, dareeraha afka	Kiniin si dhakhso leh loo sii daayo, kiniin la sii dheereeyey, dareere afka ah
Waa maxay qiyaasta caadiga ah?	10 mg 4tii saacba mar	60 mg 4 ilaa 6 saacadood kasta
Muddo intee le'eg ayaa daaweynta caadiga ah?	Muddo gaaban illaa astaamaha laga daayo	Muddo gaaban illaa astaamaha laga daayo
Ayaa si caadi ah u isticmaala daawada?	Caruurta jirta 12 sano iyo wixii ka sareeya, dadka waaweyn	Caruurta jirta 4 sano iyo wixii ka sareeya, dadka waaweyn

Xaaladaha lagu daaweeyo phenylephrine iyo pseudoephedrine

Waxaa jira qaab la isku duro oo ah phenylephrine oo loo oggolaaday in lagu daaweeyo hypotension, ama cadaadis dhiig oo aad u hooseeya, xaaladaha la xiriira naxdinta ama suuxdinta. Daawadan waxaa sida caadiga ah loo qaataa cirbad ahaan goob daryeel caafimaad halkaas oo bukaan uu kormeerayo dhakhtar iyo bixiyeyaasha kale ee daryeelka caafimaad. Waxaa sidoo kale loo isticmaalaa calaamadda-ka-baxsan, iyada oo aan la helin oggolaanshaha FDA, si loogu daaweeyo priapism-ka (kacsiga ragga oo muddo dheer socday). Foomka dawada ee loo iibsado miisaanka loo yaqaan 'phenylephrine' ayaa loo isticmaalaa sidii sanka loo suuxiyaa.

Pseudoephedrine waxaa loo oggol yahay in lagu daaweeyo ciriiriga sanka.

Xaaladda	Phenylephrine	Pseudoephedrine
Hypotension	Haa	Maaha
Qiimaynta ischemic	Off-calaamadda	Maaha
Ciriiriga sanka	Haa	Haa

Ma fenylphrine ama pseudoephedrine waxtar badan ayey leedahay?

Hal mar, pseudoephedrine asal ahaan waxay ahayd dawada kaliya ee sanka ee suuqa ku jirta. Si kastaba ha noqotee, markii iibinta badeecada ay bilaabatay in la xaddido, soo saarayaasha waxay eegeen inay dib-u-habeyn ku sameeyaan alaabadooda qayb kale oo firfircoon si ay ugu sii nagaadaan khaanadaha dukaanka oo si fudud loo iibsado. Phenylephrine wuxuu markaa noqday dawada afka ka baxda ee laga helo alaabooyinka la iibsan karo iyadoon la aadin miiska farmashiyaha si iibsashadaadu u qorto farmashiistaha.

Isticmaalka sii kordhaya ee phenylephrine wuxuu ku kallifay cilmi baarayaasha inay qiimeeyaan haddii saameynteeda qallafsan ay u xoogan tahay sida kuwa pseudoephedrine. In la kala sooco, lagu xakameeyo placebo barasho , bukaanada qaba rhinitis xasaasiyadeed xilliyeed ayaa la soo dersay manka cawska ee Qolka Vienna Challenge. Waxay heleen phenylephrine, pseudoephedrine, ama placebo si loo yareeyo astaamaha ciriiriga. Daraasadu waxay soo gabagabeysay in uusan jirin farqi weyn oo u dhexeeya phenylephrine iyo placebo. Si kastaba ha noqotee, pseudoephedrine waxay bixisay farqi weyn oo ku saabsan goynta sanka marka loo eego labadaba placebo iyo phenylephrine. Natiijooyinkani waxay soo jeedinayaan in pseudoephedrine uu yahay kan sunta ka sarreeya.

Baarayaasha qaarkood waxay leeyihiin walaac muujiyey in rabitaankeena ah in la yareeyo wax soo saarka methamphetamine iyadoo la xadidayo iibinta pseudoephedrine waxay keentay in wax soo saar liita (phenylephrine) si weyn loogu isticmaalo meeshiisa.

Marar badan, daaweynta rhinitis iyo sanka cadaadiska ayaa laga yaabaa inay waxtar badan yeeshaan haddii wakiilo kale loo isticmaalo isku-darka. Tusaale ahaan, antihistamines, waxay gaabin doontaa soo saarista xabka waxayna kordhineysaa saameynta sanka sunta.

Daboolida iyo isbarbar dhiga qiimaha ee phenylephrine iyo pseudoephedrine

Phenylephrine qaabkeeda afka ah, warqad dhakhtar iibsigu uma baahna qoro. Caadi ahaan ma daboosho Medicare ama qorshooyinka kale ee caymiska ganacsiga. Celcelis ahaan qiimaha Sudafed PE waa kudhowaad $ 6- $ 8 markii aad ka iibsaneysid miiska dukaanka, laakiin haddii dhakhtarkaagu qoro rijeeto, waxaad awoodi kartaa inaad ku buuxiso farmashiyaha ugu yaraan $ 5.96 oo kuuboon ah oo ka socota SingleCare.

Pseudoephedrine, in kasta oo loo xadiday in laga iibsado farmashiyaha, sidoo kale waa daroogada OTC. Haddii dhakhtarkaagu qoro warqad dhakhtar loogu talagalay pseudoephedrine, waxaad awoodi doontaa inaad hesho tirada ay kuu qorayaan xitaa haddii ay ka sarreyso xadka gobolka u leeyahay iibsashada miiska laga iibsado.

Pseudoephedrine caadi ahaan ma daboosho Medicare ama qorshooyinka kale ee caymiska ganacsiga, in kasta oo kuwa yar oo la xushay ay dhici karto haddii warqad dhakhtar qoro. Celceliska kharashka 24 kaniini oo ah Sudafed 30 mg ah wuxuu u dhexeeyaa $ 6- $ 10 markii la iibsado dukaanka haddii dhakhtarkaagu qoro warqad dhakhtar kuu qoray, waxaad awoodi kartaa inaad ku buuxiso jumlada guud ee farmashiyaha ugu yaraan $ 2.53 oo ay ku jiraan kuuboon ka socota SingleCare .

	Phenylephrine	Pseudoephedrine
Caadi ahaan caymiska ayaa daboolaya?	Maaha	Maaha
Caadi ahaan laga bixiyo Medicare?	Maaha	Maaha
Qiyaasta caadiga ah	18, kiniiniyada 10 mg	24, kiniiniyada 30 mg
Bixinta lacagta caadiga ah ee 'Medicare'	n / a	n / a
Qiimaha SingleCare	$ 6 +	$ 2 - $ 5

Soo qaado kaarka dhimista ee SingleCare

Saameynaha guud ee phenylephrine iyo pseudoephedrine

Phenylephrine iyo pseudoephedrine labaduba waa adonergic agonists waxayna leeyihiin qaar ka mid ah waxyeelooyinka isku midka ah, in kasta oo ay ku kala duwan yihiin isku dheelitirka alfa iyo beta-adrenergic reseptors ayaa mas'uul ka ah khilaafaadka qaarkood.

Phenylephrine iyo pseudoephedrine waxaa lagu yaqaanaa inay sababaan walwal, wareer, madax xanuun, hurdo la'aan, walwal, iyo degenaansho la'aan. Intaa waxaa dheer, pseudoephedrine waxaa loo diiwaangeliyey inuu keeno tachycardia, wadna garaac, arrhythmia, araga oo xumaada, iyo cunno xanuun. Way adag tahay in la qeexo inta jeer ee ay waxyeelooyinkan soo bixi karaan.

Bukaannada qaba dhiig karka ama xaaladaha kale ee wadnaha ee la yaqaan waa inaysan isticmaalin pseudoephedrine iyadoon talo laga helin dhakhtarkooda.

Jadwalka soo socda looma jeedin inuu noqdo liistada dhammeystiran ee dhibaatooyinka soo raaca. Waa inaad la tashataa farmashiistaha ama xirfadle daryeel caafimaad oo kale liiska oo dhammaystiran.

	Phenylephrine	Pseudoephedrine
Waxyeelada	Ma khuseysaa?	Joogtaynta	Ma khuseysaa?	Joogtaynta
Walaac	Haa	Lama qeexin	Haa	Lama qeexin
Dawakhaad	Haa	Lama qeexin	Haa	Lama qeexin
Madax xanuun	Haa	Lama qeexin	Haa	Lama qeexin
Hurdo la'aan	Haa	Lama qeexin	Haa	Lama qeexin
Dareen	Haa	Lama qeexin	Haa	Lama qeexin
Degganaansho la'aan	Haa	Lama qeexin	Haa	Lama qeexin
Tachycardia	Maaha	Lama qeexin	Haa	Lama qeexin
Baabashooyin	Maaha	Lama qeexin	Haa	Lama qeexin
Xanuunka wadnaha	Maaha	Lama qeexin	Haa	Lama qeexin
Aragga oo xumaaday	Maaha	Lama qeexin	Haa	Lama qeexin
Anorexy	Maaha	Lama qeexin	Haa	Lama qeexin

Xigasho: DailyMed (phenylephrine) DailyMed (pseudoephedrine)

Isdhexgalka daroogada ee phenylephrine iyo pseudoephedrine

Phenylephrine iyo pseudoephedrine waxay leeyihiin muuqaal aad u eg oo isdhexgal daroogo ah sababtoo ah saameyntooda adrenergic ee alfa iyo beta receptors. Alfa-xannibaadayaasha, sida tamsulosin, ayaa yareyn kara astaamaha xasaasiyadda ee labada daroogo taasoo ka dhigaysa kuwo aan waxtar badan lahayn.

MAO inhibitors, sida selegiline, iyo ergot derivatives, sida bromocriptine, ayaa laga yaabaa inay sare u qaadaan saameynta dhiig karka ee kaneecada. Tani waxay khuseysaa qof qaba dhiig-kar horay u jiray oo laga yaabo inuu ka fiirsado adeegsiga qashin-saarka. Isku-darka 'phenylephrine' ama 'pseudoephedrine' oo leh MAO inhibitors ama ergot derivatives waa la diiday.

Liistada soo socota looma jeedin inay tahay liis dhammaystiran oo ku saabsan dhammaan isdhexgalka daroogada iman kara. Fadlan la tasho farmashiistahaaga ama dhakhtarkaaga si aad uhesho liis dhameystiran iyo macluumaad dheeri ah.

Daroogada	Fasalka Daroogada	Phenylephrine	Pseudoephedrine
Alfuzosin Doxazosin Terazosin Tamsulosin	Xannibaadayaasha Alpha-1	Haa	Haa
Carvedilol Labetalol Nadolol	Xannibaadayaasha beta	Haa	Haa
Selegiline Phenelzine	Ka-joojiyeyaasha MAO	Haa	Haa
Ergotamine Bromocriptine	Alkaloids Ergot	Haa	Haa
Methyldopa Reserpine	Daawooyinka dhiig karka	Haa	Haa
Atomoxetine	Xul ah norepinephrine reuptake daawadayaasha	Haa	Haa
Amitriptyline Clomipramine Doxepin Nortriptyline	Dawooyinka lidka ku ah diiqadaha ee loo yaqaan 'Tricyclic antidepressants'	Haa	Haa

Digniinta phenylephrine iyo pseudoephedrine

Phenylephrine iyo pseudoephedrine ayaa la heli karaa iyada oo aan dhakhtar qorin waxaana guud ahaan loo tixgeliyaa inay yihiin daroogo aamin ah. Saamaynta ay ku leeyihiin nidaamka wadnaha awgood, bukaanada qaba dhiig karka iyo cudurada wadnaha waa inaysan isticmaalin daawooyinkan iyagoon ogolaasho cad ka helin dhaqtarkooda. Daawooyinkan waxaa loogu talagalay in lagu isticmaalo muddo-gaaban gargaarka loo yaqaan 'rhinitis' ba'an iyo cadaadiska sanka. Bukaannada la kulma astaamahan in ka badan toddobo maalmood, ama ku dhaca qandho, waa inay la tashadaan dhakhtar.

Phenylephrine ayaa ku jirta uurka qaybta C taas oo macnaheedu yahay in daraasaadka lagu sameeyay xayawaanku ay saameyn xun ku yeesheen uurjiifka. Marka daroogadu tahay nooca C, waxaa jiri kara xaalado qaarkood oo faa'iidada bukaanka uurka leh ay ka weyn tahay halista, iyo in phenylephrine aan loo isticmaalin ogolaansho la'aan dhakhtarkaaga. Pseudoephedrine waa qaybta uurka B taas oo macnaheedu yahay in daraasaadka xayawaanku aysan muujinin waxyeello uurjiifka. Pseudoephedrine waxaa loo arkaa mid badbaado leh in la qaato marka uurka la leedahay ka dib markii aad la tashatay dhakhtarkaaga. Pseudoephedrine waa, si kastaba ha noqotee, in laga fogaado saddexda bilood ee ugu horreysa.

Su'aalaha badanaa la isweydiiyo ee ku saabsan phenylephrine iyo pseudoephedrine

Waa maxay phenylephrine?

Phenylephrine waa dawad sanka ka soo baxda oo lagu iibiyo 5 mg iyo 10 mg kiniin ah, iyo waliba xal afka ah. Waxaa sidoo kale lagu heli karaa qaab lagu durayo oo kaliya loo isticmaalo goobta bukaan-jiifka ee xirfadlayaasha caafimaadku u leeyihiin cadaadiska dhiigga oo hooseeya. Phenylephrine waa la iibsan karaa iyada oo aan la xadidin ama aan la qorin macluumaadka iibsadaha.

Waa maxay pseudoephedrine?

Pseudoephedrine waa daawo-yare sanka laga iibsado oo laga heli karo 30 mg iyo 60 mg kiniin ah, iyo sidoo kale 120 mg iyo 240 mg kiniin dheereyn ah. Waxaa sidoo kale loo heli karaa xal afka ah. Iibsashada Pseudoephedrine waa in lagu sameeyaa farmashiyaha macluumaadka iibsigana waa in lagu qoro keydka macluumaadka. Xadka iibsiga waxaa dejiyay tilmaamaha gobolka iyo federaalka.

Phenylephrine ama pseudoephedrine ma isku midbaa?

Phenylephrine iyo pseudoephedrine labaduba waa adonergic agonists. Phenylephrine wuxuu asal ahaan leeyahay xiriir kaliya soo dhaweynta alfa-adrenergic, halka pseudoephedrine ay leedahay xiriir labada alfa iyo beta-adrenergic. Noocyada saameyntooda dhinaca ayaa aad isugu eg.

Ma phenylephrine ama pseudoephedrine ayaa ka fiican?

Daraasaduhu waxay muujiyeen in pseudoephedrine ay aad uga waxtar badan tahay phenylephrine. Saamaynta dawada Phenylephrine ayaa laga yaabaa inaanay si weyn uga duwanayn tan placebo. Saameynta labada daroogo ayaa lagu kordhin karaa iyadoo isla mar ahaantaana loo isticmaalo alaabooyin kale oo saameeya rhinitis, sida antihistamines.

Ma isticmaali karaa phenylephrine ama pseudoephedrine inta aan uurka leeyahay?

Phenylephrine looma isticmaali karo markay uurka leedahay ilaa iyo in waxtarka hooyadu ka badan yahay halista. Pseudoephedrine waxaa loo arkaa mid amni ah in la qaato ka dib saddexda bilood ee ugu horreysa. Had iyo jeer la tasho dhakhtarkaaga ka hor intaadan qaadin sanka suuxdinta markaad uurka leedahay.

Ma ku isticmaali karaa phenylephrine ama pseudoephedrine aalkolo?

Phenylephrine iyo pseudoephedrine waa badbaado in la qaato haddii ay aalkolo cabayaan.

Fenylephrine miyuu kiciyaa?

Phenylephrine wuxuu kiciyaa soo-dhoweeyaasha alfa-adrenergic taas oo ka dhigi karta inay mas'uul ka tahay saameynta habka dhexe ee neerfayaasha sida xasilloonida, walwalka, iyo hurdo la'aan. Waxaa loo maleynayaa in aysan sababi karin saameynta ilaa heerka pseudoephedrine uu sameeyo, hase yeeshe.

Yaan qaadanayn phenylfrine?

Bukaanka qaba dhiig karka, cudurada wadnaha ee horay u jiray, ama xaaladaha kale ee wadnaha waa inaysan qaadan phenylephrine ogolaansho la'aan dhaqtarkooda. Waxaa jira ikhtiyaarro kale oo wax baabi'iya, sida buufinta sanka, oo laga yaabo inay ku habboon tahay dadkan. Haweenka uurka lihi waa inay la tashadaan dhakhtar kahor intaysan isticmaalin fenylphrine.

Fenylephrine ma yahay wax baabiiya wanaagsan?

Daraasaduhu waxay muujiyeen in phenylephrine ay ka liidato, ama ka waxtar yar tahay, ka yareyn badan tahay daawada loo yaqaan 'pseudoephedrine'. Xaqiiqdii, ma bixin karto wax faa'iido ah tan placebo.