Metoprolol tartrate iyo metoprolol succinate: Kala duwanaanshaha, isku ekaanshaha, iyo yaa kuu fiican adiga
Daroogada Vs. SaaxiibDulmarka daroogada & kala duwanaanshaha ugu weyn | Xaaladaha la daweeyay | Wax ku oolnimada | Caymiska caymiska iyo isbarbardhiga qiimaha | Dhibaatooyinka ay keento | Isdhexgalka daroogada | Digniinta | Su'aalaha
Haddii aad isku aragtay wadne qabad ama aad hadda la nooshahay dhiig kar, dhakhtarkaagu wuxuu kuu qori karaa daawo sida metoprolol tartrate (Lopressor) ama metoprolol succinate (Toprol XL). In kasta oo labada daroogo ay ku jiraan maaddooyin firfircoon oo isku mid ah, waxaa loo isticmaali karaa siyaabo kala duwan.
Labadan metoprolol tartrate iyo metoprolol succinate labaduba waxay ka tirsan yihiin nooc daroogo ah oo loo yaqaan beta beta . Waxay mararka qaarkood sidoo kale loo yaqaan 'beta-1 xayirayaasha xayeysiinta adrenoceptor iyo beta antagonists.
Daawooyinkani waxay ku shaqeeyaan iyagoo xakameynaya saameynta hormoonnada sida epinephrine iyo norepinephrine ee nidaamka dareenka naxariista leh. Nidaamka neerfaha ee naxariista leh ayaa mas'uul ka ah jawaabta dagaalka ama duulimaadka caadiga ah. Metoprolol wuxuu kaa caawin karaa yareynta culeyska wadnaha, dejinta xididdada dhiigga si loo yareeyo cadaadiska dhiigga, loona yareeyo xanuunka laabta.
Maxay ku kala duwan yihiin waxyaabaha u dhexeeya metoprolol tartrate iyo metoprolol succinate?
Farqiga ugu weyn ee udhaxeeya metoprolol tartrate (Waa maxay metoprolol tartrate?) Iyo metoprolol succinate (Waa maxay metoprolol succinate?) Ayaa kujira qaabkooda. Metoprolol tartrate waa nooca si deg deg ah loo sii daayo ee metoprolol halka metoprolol succinate uu yahay nooca sii-deynta la dheereeyay. Tani waxay ka dhigan tahay in metoprolol succinate la sii daayo waqti ka dib jirka taasoo u horseedeysa saameyn muddo dheer qaadatay.
Metoprolol tartrate waxay u baahan kartaa in la qaato dhowr jeer maalintii. Metoprolol succinate waa la qaadan karaa hal mar maalintii maxaa yeelay waxay ka sii dheereysaa foomka tartrate-ka. Metoprolol succinate sidoo kale waxaa loo isticmaali karaa carruurta da'doodu tahay 6 sano iyo wixii ka weyn halka metoprolol tartrate loo isticmaali karo oo keliya dadka waaweyn.
| Farqiga ugu weyn ee u dhexeeya metoprolol tartrate iyo metoprolol succinate | ||
|---|---|---|
| Metoprolol Tartrate | Metoprolol Succinate | |
| Fasalka daroogada | Xannibaadaha beta | Xannibaadaha beta |
| Summad / astaan guud | Nooc nooc iyo nooc guud ah ayaa la heli karaa | Nooc nooc iyo nooc guud ah ayaa la heli karaa |
| Waa maxay magaca sumaddu? | Lopressor | Toprol XL |
| Waa noocee (yada) daroogadu soo gasho? | Kiniin afka ah | Kiniin afka ah, sii-deyn dheeri ah |
| Waa maxay qiyaasta caadiga ah? | 100 mg ilaa 400 mg maalin kasta qiyaaso kala qaybsan | 100 mg hal mar maalintii |
| Muddo intee le'eg ayaa daaweynta caadiga ah? | Isticmaalka muddada-gaaban ama muddada-dheer ah sida uu takhtarku ku faro | Isticmaalka muddada-gaaban ama muddada-dheer ah sida uu takhtarku ku faro |
| Ayaa si caadi ah u isticmaala daawada? | Dadka waaweyn | Dadka waaweyn iyo carruurta jirta 6 sano iyo wixii ka weyn |
Ma dooneysaa qiimaha ugu fiican ee metroprolol tartrate?
Saxiix digniinta qiimaha metoprolol tartrate oo ogow goorta sicirku isbeddelo!
Hel digniinta qiimaha
Xaaladaha ay daweeyaan metoprolol tartrate iyo metoprolol succinate
Noocyada loo yaqaan 'tartrate' iyo 'succinate metoprolol' waa FDA-ogolaatay in lagu daaweeyo dhiig karka (dhiig karka) iyo laabta xanuun (angina pectoris).
Metoprolol tartrate sidoo kale FDA ayaa loo ansixiyay daaweyn isla marka la gaaro a wadne qabad (infarction myocardial daran). Qaadashada marinka metoprolol kadib wadne qabad waxay kaa caawin kartaa yareynta halista dhacdooyinka wadnaha iyo xididdada wadnaha iyo dhimashada gaar ahaan kuwa qaba cudurka halbowlayaasha wadnaha. Daaweyntu badanaa waa inay bilaabataa 3 ilaa 10 maalmood gudahood ka dib wadno qabadka.
Marka lagu daro dhiig karka iyo xanuunka laabta, metoprolol succinate sidoo kale waa FDA-ogolaatay in lagu daaweeyo wadnaha oo xirma . Si gaar ah, metoprolol succinate wuxuu daaweeyaa wadno xanuun joogto ah oo ah Ururka Wadnaha ee New York fasalka II ama III. Marka loo eego qaadasho maalinle ah, metoprolol succinate waxay hagaajin kartaa natiijooyinka waxayna yareyn kartaa halista dhimashada bukaannada wadnaha istaaga.
Off-calaamadda Isticmaalka metoprolol waxaa ka mid ah tachycardia supraventricular (garaaca wadnaha oo aan caadi ahayn) iyo duufaanta tayroodhka (xaalad khatar ah oo ka dhalata soosaarka xad dhaafka ah ee hoormoonka tayroodhka). Adeegsiga kale ee calaamada ka baxsan waxaa ka mid noqon kara daaweynta wadnaha oo aan caadi ahayn (arrhythmia) iyo walaaca waxqabadka .
| Xaaladda | Metoprolol Tartrate | Metoprolol Succinate |
| Dhiig kar | Haa | Haa |
| Xabad xanuun joogto ah | Haa | Haa |
| Wadno xanuun daran | Haa | Off-calaamadda |
| Wadne istaag | Off-calaamadda | Haa |
| Tachycardia ka sarreeya | Off-calaamadda | Off-calaamadda |
| Duufaanta tayroodhka | Off-calaamadda | Off-calaamadda |
| Arrhythmia | Off-calaamadda | Off-calaamadda |
| Waxqabadka walaaca | Off-calaamadda | Off-calaamadda |
Ma metoprolol tartrate ama metoprolol succinate ayaa waxtar badan leh?
Metoprolol tartrate iyo metoprolol succinate labaduba waxay la mid yihiin waxtarka daaweynta dhiig karka iyo xanuunka xabadka ee joogtada ah. Si kastaba ha noqotee, metoprolol tartrate waxay noqon kartaa mid wax ku ool ah daaweyn ahaan wadno xanuunka wadnaha halka metoprolol succinate ay ka waxtar badan tahay daaweynta wadnaha oo raaga.
Caafimaad tijaabooyin waxay muujiyeen in maadada metoprolol ay waxtar u leedahay dhiig karka iyo kahortaga natiijooyinka xun kadib wadno qabad. Taas bedelkeeda, daraasado ay ka mid yihiin tijaabada Merit-HF ayaa muujiyay in metoprolol succinate ay ka sareyso metoprolol tartrate qalbi jabka joogtada ah.
Metoprolol succinate wuxuu yareyn karaa booqashooyinka isbitaalada ee soo noqnoqda iyo dhimashada wadnaha oo istaaga. Si kastaba ha noqotee, carvedilol , beta kale oo caadi ah, ayaa xitaa ka waxtar badan metoprolol succinate, sida ku cad tijaabada lagu daabacay Lancet .
Sababtoo ah tartrate metoprolol waxaa la qaadaa dhowr jeer maalintii oo dhan, heerarka daroogada ee jirka ma noqon karaan kuwo isku mid ah. Tani waxay sababi kartaa waxyeelo badan iyo dulqaad yar marka loo eego foomka succinate-ee sii-daaya. Mid falanqaynta waxay ogaadeen in dhibaatooyinka soo raaca sida garaaca wadnaha oo gaabis ah (bradycardia) ay u badan tahay inay ku dhacaan iyadoo si dhakhso leh loo sii daayo tartrate metoprolol.
Daboolida iyo qiimaha isbarbar dhiga metoprolol tartrate iyo metoprolol succinate
Metoprolol tartrate waxaa loo iibsan karaa iyada oo ah daawo dhakhtar qoro oo inta badan daboosho Medicare iyo qorshooyinka kale ee caymiska. Caymis la'aan, celceliska qiimaha lacagta caddaanka ah ee metoprolol tartrate waa $ 5. Kaararka dhimista SingleCare waxaa loo isticmaali karaa farmasiyada kaqeybgalaya si loo yareeyo qiimaha daawadan. Waxaad ka heli kartaa qiimo ku dhow $ 4 oo leh kuuboon keyd ah.
Metoprolol succinate ama sii-daynta metoprolol ayaa loo heli karaa iyada oo ah daawo guud oo ay daboosho inta badan Medicare iyo qorshayaasha caymiska. Generic metoprolol succinate waxay u badan tahay in la daboolo marka loo eego magaca magaca Toprol XL. Celceliska qiimaha tafaariiqda ee guud ahaan Toprol XL waa illaa $ 56. Ka hubi farmashiyahaaga si aad u ogaato haddii aad wax badan ku keydin karto kaarka keydka ee SingleCare. Haddii la aqbalo, waxaad yareyn kartaa kharashka $ 9.
| Metoprolol Tartrate | Metoprolol Succinate | |
| Caadi ahaan caymiska ayaa daboolaya? | Haa | Haa |
| Caadi ahaan laga bixiyo Medicare? | Haa | Haa |
| Qiyaasta caadiga ah | 50 mg kiniin ah | 100 mg kiniin ah |
| Bixinta lacagta caadiga ah ee 'Medicare' | $ 0- $ 65 | $ 0- $ 20 |
| Qiimaha SingleCare | $ 4 | $ 9 |
Soo qaado kaarka dhimista farmasiga
Waxyeelooyinka guud ee loo yaqaan 'metoprolol tartrate' iyo 'metoprolol succinate'
Metoprolol tartrate iyo metoprolol succinate waxay sababi karaan waxyeelo isku mid ah. Dhibaatooyinka ugu badan ee metoprolol waxaa ka mid ah daal ama daal, dawakhaad, niyad jab, neefta oo ku qabata (dyspnea), iyo wadnaha oo gaabis ah (bradycardia). Waxyeelooyinka kale waxaa ka mid ah shuban, lallabo, matag, iyo afka oo qallala.
Dareen-celinta xasaasiga ah sida furuuruc ama cuncun ayaa sidoo kale dhici kara marka la qaadanayo nooc kasta oo metoprolol ah. Iyada oo ku saleysan Calaamadda FDA , Tartrate metoprolol waxay u badan tahay inay keento waxyeelo gaar ah.
| Metoprolol Tartrate | Metoprolol Succinate | |||
| Waxyeelada | Ma khuseysaa? | Joogtaynta | Ma khuseysaa? | Joogtaynta |
| Daal | Haa | 10% | Haa | > 2% |
| Dawakhaad | Haa | 10% | Haa | > 2% |
| Firiiric | Haa | 5% | Haa | > 2% |
| Niyad jab | Haa | 5% | Haa | > 2% |
| Shuban | Haa | 5% | Haa | > 2% |
| Neefta oo kugu yaraata | Haa | 3% | Haa | > 2% |
| Garaaca wadnaha oo gaabis ah | Haa | 3% | Haa | > 2% |
| Af qalalan | Haa | 1% | Haa | * lama soo sheegin |
| Lallabbo | Haa | 1% | Haa | * |
| Laab xanuun | Haa | 1% | Haa | * |
| Calool fadhiga | Haa | 1% | Haa | * |
Tani ma noqon karto liis dhameystiran. La tasho dhakhtarkaaga ama farmashiistaha wixii dhibaato ah ee ka imaan kara.
Xigasho: DailyMed (metoprolol tartrate) , DailyMed (metoprolol succinate)
Isdhexgalka daroogada ee metoprolol tartrate iyo metoprolol succinate
Metoprolol tartrate iyo metoprolol succinate waxay la macaamili karaan dawooyin badan oo isku mid ah. Daawooyinka kale ee leh ficilo la mid ah ama saameynaya dheef-shiid kiimikaadka beta beta waxay la falgeli karaan labada nooc ee metoprolol.
Metoprolol waa inaan lagu qaadan dawooyinka yareysa catecholamine. Qaadashada daawooyinkan waxay kordhin kartaa saameynta beta beta waxayna sababi kartaa dhacdooyin xun sida cadaadiska dhiigga oo hooseeya ( hypotension ) iyo wadnaha oo gaabis ah (bradycardia). Dhibaatooyinka kale ee xun waxaa ka mid noqon kara dawakhaad iyo suuxdin.
Metoprolol waxaa si xoog leh u farsameeya enzyme-ka 'CYP2D6'. Sidaa darteed, daawooyinka xakameynaya enzyme-kan waxay sababi karaan heerarka metoprolol ee jirka. Kordhinta heerarka metoprolol waxay kordhin kartaa halista waxyeelada xun.
Digoxin iyo daawooyinka loo yaqaan 'calcium channel blockers' ayaa laga yaabaa inay yeeshaan saameyn dheeraad ah marka la siiyo metoprolol. Qaadashada mid kamid ah daawooyinkan metoprolol waxay sababi kartaa waxyeelo dhanka wadnaha ah.
| Daroogada | Fasalka Daroogada | Metoprolol Tartrate | Metoprolol Succinate |
| Reserpine Tetrabenazine | Dawada yareysa Catecholamine | Haa | Haa |
| Quinidine Fluoxetine Fluvoxamine Sertraline Bupropion Paroxetine Propafenone Haloperidol Diphenhydramine Hydroxychloroquine Terbinafine | CYP2D6 horjoogsade | Haa | Haa |
| Digoxin | Glycoside wadnaha | Haa | Haa |
| Diltiazem Verapamil | Xannibaadda kanaalka Calcium | Haa | Haa |
| Clonidine Guanethidine Betanidine | Wakiilka Alpha-adrenergic | Haa | Haa |
Tani ma noqon karto liistada dhameystiran ee dhammaan isdhexgalka daroogada ee suurtogalka ah. La tasho dhakhtar dhammaan daawooyinka aad qaadan karto.
Digniinta tartrate metoprolol iyo metoprolol succinate
Labada metroprolol tartrate iyo metoprolol succinate labadaba yaan loo joojin si kadis ah. Haddii daaweynta metoprolol si lama filaan ah loo joojiyo, dadka qaar waxaa laga yaabaa inay la kulmaan halista sare ee wadno-qabadka, aan caadiga ahayn garaaca wadnaha , iyo laab xanuun. Khatarta dhacdooyinkan ayaa ku badan kuwa qaba cudurrada wadnaha ee salka ku haya.
Beta blockers sida metoprolol looma isticmaali karo qof kasta oo leh xaaladaha soo socda:
- Bradycardia daran
- Xannibaadda wadnaha ee ka weyn heerka koowaad
- Naxdinta wadnaha
- Wadne qabad aan kala go 'lahayn
- Cillada sanka ee jiran iyada oo aaladda wadnaha la galiyo
- U nuglaanshaha walax kasta oo ka mid ah daawooyinkan
La tasho dhakhtar si aad u aragto haddii aad yeelan karto mid ka mid ah xaaladahaas ka hor intaadan bilaabin daaweynta.
Beta blockers waxay qarin karaan astaamaha iyo astaamaha hypoglycemia, ama sonkorta dhiiga oo hooseysa. Kuwa sonkorowga qaba waxay u baahan karaan inay la socdaan sonkorta dhiigooda inta ay qaadanayaan beta beta.
Su'aalaha badanaa la isweydiiyo ee ku saabsan metoprolol tartrate iyo metoprolol succinate
Waa maxay metroprolol tartrate?
Metoprolol tartrate waa magaca guud ee Lopressor. Waa xanibaada beta ee loo isticmaalo in lagu daaweeyo dhiig karka iyo xanuun laabta oo joogto ah. Waxaa sidoo kale loo oggol yahay daaweynta wadno-qabad ba'an si loo yareeyo halista dhimashada.
Waa maxay metoprolol succinate?
Metoprolol succinate waxaa sidoo kale loo yaqaan magaca astaanta Toprol XL. Waa foomka sii-deynta ee metoprolol. Metoprolol succinate waxaa loo oggol yahay inuu daaweeyo dhiig karka, xanuunka xabadka oo raaga, iyo ciriiriga wadnaha oo istaaga .
Tartarka metoprolol iyo metoprolol miyey isku mid yihiin?
Maya. Metoprolol tartrate waa kiniin si dhakhso leh loo sii daayo halka metoprolol succinate uu yahay kiniin la sii daayay. Waxaa loo isticmaali karaa siyaabo kala duwan.
Ma metroprolol tartrate ama metoprolol succinate ayaa ka fiican?
Metoprolol tartrate iyo metoprolol succinate labadaba waa kuwo waxtar leh iyadoo kuxiran xaalada la daweynayo. Metoprolol succinate ayaa waxtar badan u leh daaweynta wadnaha oo istaaga. Metoprolol succinate sidoo kale way u badnaan kartaa inuu sababo waxyeelo qaar.
Ma isticmaali karaa metroprolol tartrate ama metoprolol succinate intaan uurka leeyahay?
Metoprolol waa in la isticmaalaa oo keliya inta uurka la leeyahay haddii faa'iidooyinka si cad ay uga culus yihiin halista. Ma ahan daraasado ku filan oo la sameeyay si loo muujiyo in daawooyinkaani ay 100% ammaan yihiin inta lagu jiro uurka. La tasho dhakhtar haddii aad uur leedahay ama aad naas nuujiso.
Ma isticmaali karaa metartorolol tartrate ama metoprolol oo khamri ku kooban?
Cabitaanka khamriga intaad qaadanayso metoprolol waxay kordhin kartaa halista lulmidda iyo dawakhaad. Guud ahaan laguma talinayo in la isticmaalo metoprolol aalkolo .
Miyaad ka beddeli kartaa metoprolol tartrate oo aad ku koobnaan kartaa?
Xaaladaha qaarkood, tartrate metoprolol waxaa loo beddeli karaa metoprolol succinate. Metoprolol succinate ayaa laga doorbidi karaa dawadiisa hal mar maalin kasta. La tasho dhakhtar si aad u go'aamiso xulashooyinkaaga daaweyn markaad u beddeleyso daawooyinka.
Goorma ayey tahay inaadan qaadan metoprolol?
Metoprolol waa in aan laqaadanin hadii aad dareento heerar garaaca wadnaha oo aad uyar, cadaadis dhiig oo hooseeya, ama wadno xanuun daran. Waa muhiim inaad kala hadasho takhtarkaaga taariikhdaada caafimaad si aad u ogaato inaad metoprolol tahay iyo in kale.
Maxaan iska ilaaliyaa inta aan qaadanayo metoprolol?
Aalkolada iyo daawooyinka qaarkood waa in laga fogaadaa inta la qaadanayo metoprolol. Daawooyinka qaarkood oo ay ku jiraan kaalshiyamka kanaalka kaaliyayaasha, qaarkood dawooyinka lidka diiqadda , iyo kuwa looga baaraandego si la mid ah metoprolol waxay kordhin kartaa halista waxyeellooyinka xun ee metoprolol.
Metoprolol ma tahay daawo khatar sare leh?
Haa. Metoprolol waxaa loo tixgelin karaa inay tahay daawo khatar sare leh. Marka si khaldan loo isticmaalo, metoprolol wuxuu sababi karaa waxyeelo weyn.
