Trintellix vs. Prozac: Kala duwanaanshaha, isku ekaanshaha, iyo yaa kuu fiican adiga
Daroogada Vs. SaaxiibDulmarka daroogada & kala duwanaanshaha ugu weyn | Xaaladaha la daweeyay | Wax ku oolnimada | Caymiska caymiska iyo isbarbardhiga qiimaha | Dhibaatooyinka ay keento | Isdhexgalka daroogada | Digniinta | Su'aalaha
Weydii asxaabtaada kuugu dhow ama qoyskaaga waxaadna ogaan doontaa in ku dhowaad qof walba uu la soo kulmay niyad jab waqti ka mid ah noloshooda. Markuu niyad-jabka isu rogo xaalad daciif ah oo muddo dheer socota, waxay si weyn u saameyn kartaa nolosha dhinac walba. Sida laga soo xigtay NIH , Cudurka weyn ee niyadjabka (MDD) wuxuu saameeyaa qiyaastii 17.3 milyan oo qaangaar Mareykan ah. Haddii lagaa helay niyad jab weyn, waxaa laguu qori karaa daawo sida Trintellix ama Prozac.
Trintellix (vortioxetine) iyo Prozac (fluoxetine) waa laba dawooyinka lidka diiqadda ku shaqeeya siyaabo la mid ah. Labada daawoba waxay kordhiyaan saameynta serotonin, neurotransmitter muhiim u ah maskaxda. Trintellix iyo Prozac waxay xannibayaan dib u soo celinta serotonin si markaa loo helo si loo xakameeyo niyadda. In kasta oo labada daroogo isku mid yihiin, haddana waxay ku kala duwan yihiin qiimaha, waxyeellooyinka soo gaara, iyo sida loo isticmaalo.
Maxay yihiin farqiga ugu weyn ee u dhexeeya Trintellix iyo Prozac?
Trintellix waxaa kaliya loo heli karaa iyada oo ah magac magac ku caan ah halka Prozac si ballaaran loogu heli karo qaab guud. Sababtoo ah ma jiro wax beddel guud ah oo loogu talagalay Trintellix, way ka qaalisan tahay iibsiga.
In kasta oo daawooyinka lidka ku ah diiqadda loo isticmaali karo daaweyn loogu talagalay cudurka weyn ee niyadjabka, Prozac sidoo kale waxaa loo isticmaali karaa in lagu daaweeyo cudurada kale ee caafimaadka maskaxda. Tusaale ahaan, Prozac wuxuu kaloo daaweyn karaa cillad qasab-qasab ah (OCD) iyo xaalado kale (eeg Xaaladaha ay daweeyaan Trintellix iyo Prozac hoosta).
Prozac wuxuu ka tirsan yahay nooc ka mid ah dawooyinka lidka diiqadda ee loo yaqaan 'serotonin reuptake inhibitors' (SSRIs) halka Trintellix laguma darin fasal gaar ah oo ka mid ah antidepressant. Trintellix wuxuu ka tirsan yahay koox ka mid ah dawooyinka lidka diiqadda.
Trintellix waxaa loo qaataa kiniin hal maalinle ah. Prozac waxaa badanaa la qaataa hal mar maalintii inkasta oo ay waliba u timaado kiniin todobaadle ah oo kiniin ah. Si kastaba ha noqotee, magaca caanka ah ee loo yaqaan 'Prozac' kiniiniga toddobaadlaha ah ayaa la joojiyay. Taa baddalkeeda, dhakhaatiirta qaar ayaa kuu qori kara foomka guud ee dib-u-sii-deynta ee Prozac halkii.
| Farqiga ugu weyn ee u dhexeeya Trintellix iyo Prozac | ||
|---|---|---|
| Trintellix | Prozac | |
| Fasalka daroogada | Dawada lidka ku ah Kale | Dawada lidka ku ah Xakamaynta serotonin xulashada (SSRI) |
| Summad / astaan guud | Magaca sumadda oo keliya | Nooc nooc iyo nooc guud ah ayaa la heli karaa |
| Waa maxay magaca guud? | Vortioxetine | Fluoxetine |
| Waa noocee (yada) daroogadu soo gasho? | Kiniin afka ah | Kaabsal afka ah |
| Waa maxay qiyaasta caadiga ah? | 10 mg hal mar maalintii | 20 mg hal mar maalintii |
| Muddo intee le'eg ayaa daaweynta caadiga ah? | Muddo-gaaban ama muddo-dheer ah sida uu takhtarku ku faro | Muddo-gaaban ama muddo-dheer ah sida uu takhtarku ku faro |
| Ayaa si caadi ah u isticmaala daawada? | Dadka waaweyn ee jira 18 sano iyo wixii ka weyn | Dadka qaangaarka ah iyo carruurta 8 sano iyo ka weyn (loogu talagalay daaweynta MDD) |
Xaaladaha ay daweeyaan Trintellix iyo Prozac
Trintellix waa FDA-ogolaatay in lagu daaweeyo cillad weyn oo niyadjab leh. Cudurka weyn ee niyadjabka, oo sidoo kale loo yaqaan niyadjab weyn ama niyadjab caafimaad, ayaa lagu gartaa astaamaha sida dareenka joogtada ah ee murugada ama rajo beelka iyo sidoo kale tamarta oo yaraata, rabitaanka cuntada, feejignaanta, iyo isku kalsoonaanta. Niyad jab weyn ayaa sidoo kale u horseedi kara fikradaha isdilka iyo isbeddelada kale ee dhaqanka.
Prozac sidoo kale waa FDA loo ogolaaday in lagu daaweeyo jahwareerka weyn ee niyadjabka. Prozac sidoo kale waxaa loo isticmaali karaa daaweyn loogu talagalay xanuunada kale ee caafimaadka maskaxda sida cillad qasab ah oo qasab ah (OCD) iyo khalkhal argagax. Prozac sidoo kale waa loo isticmaali karaa in lagu daaweeyo Bulimia nervosa , cilad daran oo xagga cunnada ah oo ku lug leh cunnida xad-dhaafka ah iyo nadiifinta. Markii loo isticmaalo daawada dhimirka ee loo yaqaan Zyprexa (olanzapine), Prozac wuxuu daaweyn karaa dhacdooyinka niyadjabka ee cudurka laba-cirifoodka iyo sidoo kale niyad-jabka daaweynta u adkeysta.
Labada daroogo ayaa mararka qaarkood loo isticmaali karaa calaamado ka baxsan walwalka iyo cilado kale sida ADHD . Ka eeg shaxda hoose adeegsiga kale ee calaamada ka baxsan ee daroogadan.
| Xaaladda | Trintellix | Prozac |
| Cudurka weyn ee niyadjabka | Haa | Haa |
| Cilad qasab ah oo qasab ah (OCD) | Off-calaamadda | Haa |
| Ciladda argagaxa | Off-calaamadda | Haa |
| Niyad jab la xiriira cudurka laba-cirifoodka | Maaha | Haa |
| Bulimia nervosa | Maaha | Haa |
| Cillad-xumo cunista | Maaha | Off-calaamadda |
| Walaac | Off-calaamadda | Off-calaamadda |
| Ciladda feejignaanta yaraanta feejignaanta (ADHD) | Off-calaamadda | Off-calaamadda |
Trintellix ama Prozac waxtar badan ma leedahay?
Trintellix iyo dawooyinka lidka ku ah diiqadda ee SSRI sida Prozac ayaa la muujiyey inay wax ku ool u yihiin yareynta astaamaha niyad-jabka marka la barbar dhigo daaweyn la'aan. Sababtoo ah Trintellix waa dawo cusub oo cusub marka loo eego Prozac, hadda ma jiraan daraasado si toos ah isu barbar dhigaya labada.
Sida laga soo xigtay daraasadaha caafimaadka , vortioxetine waxay wax ku ool u tahay daaweynta xanuunka weyn ee niyadjabka ee kuwa aan la kulmin horumarin daawooyinka kale ee diiqadda. Saddex daraasadood oo laga sameeyay barkad 27 daraasadood ah ayaa lagu ogaaday in vortioxetine ay wanaajisay niyadjabka dadka aan la kulmin gargaarka daawooyinka sida Wellbutrin SR (bupropion SR) iyo Effexor (venlafaxine).
Mid ka mid ah barasho , daaweynta lidka diiqadda ee fluoxetine, maaddada firfircoon ee Prozac, waxay hagaajisay tayada guud ee nolosha kuwa qaba niyad-jabka iyo / ama walwalka walaaca. In kasta oo daraasaddani aysan si gaar ah ugu jirin Trintellix, haddana waxaa ku jiray SSRIs kale sida Lexapro (escitalopram) iyo Paxil (paroxetine).
Daaweynta niyad-jabka ayaa si gaar ah loo shakhsiyeeyey. Waa muhiim inaad la hadasho dhakhtarkaaga si aad u go'aansato ikhtiyaarka daaweynta ugu fiican ee adiga kugu habboon.
Daboolida iyo isbarbar dhiga qiimaha ee Trintellix iyo Prozac
Trintellix waxaa loo iibsan karaa 5 mg, 10 mg, ama 20 mg kiniin ah. In kasta oo uusan weli jirin nooc guud oo la heli karo weli, Trintellix waxaa daboolaya Medicare Qaybta D iyo qorshooyinka caymiska badankood. Celceliska qiimaha tafaariiqda ee Trintellix oo aan caymis lahayn ayaa socon kara $ 400- $ 600. Haddii aad raadineyso inaad ka iibsato Trintellix farmasigaaga maxalliga ah, waad hubin kartaa inaad fiiriso haddii ay aqbalayaan kaarka keydka ee SingleCare. SingleCare-ka waxaad hoos ugu dhigi kartaa qiimaha lacagta caddaanka ah illaa $ 377.35 iyadoo kuxiran farmasiga aad aadeyso.
Prozac waxaa laga iibsan karaa labadaba nooc iyo noocyo guud. Haddii laguu qoro Prozac, dhakhtarkaagu wuxuu u badan yahay inuu kuu qoro nooca fluoxetine-ka guud. Sida Trintellix iyo dawooyinka lidka ku ah walwalka, Prozac waxaa daboola inta badan Medicare iyo qorshayaasha caymiska. Celceliska qiimaha tafaariiqda ee guud ahaan Prozac waa ilaa $ 100. Kaadhka dhimista ee SingleCare, waxaad filan kartaa inaad bixiso ugu yaraan $ 4.
| Trintellix | Prozac | |
| Caadi ahaan caymiska ayaa daboolaya? | Haa | Haa |
| Caadi ahaan waxaa daboolaya Medicare? | Haa | Haa |
| Qiyaasta caadiga ah | 10 mg kiniin ah (30-maalin sahay) | 20 mg kiniin ah (30-maalin sahay) |
| Bixinta lacagta caadiga ah ee 'Medicare' | $ 40.19 | $ 0- $ 12 |
| Qiimaha SingleCare | $ 377.35 | $ 4 |
Dhibaatooyinka guud ee Trintellix iyo Prozac
Trintellix iyo Prozac, sida kuwa kale ee lidka diiqadda, waxay sababi karaan isku mid waxyeelo s ee saameeya habka dheef-shiidka, habka neerfaha ee dhexe (CNS), iyo jirka guud ahaan.
Dhibaatooyinka ugu badan ee loo yaqaan 'Trintellix' waxaa ka mid ah lallabbo, shuban, dawakhaad, iyo af qalalan. Dhibaatooyinka ugu badan ee Prozac waxaa ka mid ah lallabbo, madax xanuun, hurdo la'aan, walwal, walwal, iyo shuban. Dhibaatooyinka ay keento labada daroogo midkoodna inta badan waa khafiif oo wuu baaba'aa isticmaalka joogtada ah kadib
Labadaba daawada niyadjabka waxay sidoo kale sababi karaan waxyeelo dhanka galmada ah sida cillad galmo ama libido yaraatay (galmo galmo).
Prozac wuxuu sababi karaa miisaan lumis taas oo u muuqan karta cuncun mararka qaarkood. Trintellix looma muujin inay sababi karto isbedel kasta oo miisaanka ah sida miisaanka oo kordha ama miisaan lumis.
Dhibaatooyinka kale ee halista ah ee labada daroogo midkood waxaa ka mid noqon kara xasaasiyad ama xasaasiyad xasaasiyadeed. Haddii aad isku aragto dhibaato neefsasho, finan daran, ama finan, si dhakhso leh u raadi daryeel caafimaad.
| Trintellix | Prozac | |||
| Saamaynta Side | Ma khuseysaa? | Joogtaynta | Ma khuseysaa? | Joogtaynta |
| Lallabbo | Haa | 32% | Haa | 22% |
| Madax xanuun | Haa | * lama soo sheegin | Haa | kow iyo labaatan% |
| Hurdo la'aan | Maaha | - | Haa | 19% |
| Dareen | Maaha | - | Haa | 13% |
| Walaac | Maaha | - | Haa | 12% |
| Shuban | Haa | 7% | Haa | kow iyo toban% |
| Dawakhaad | Haa | 9% | Haa | 9% |
| Af qalalan | Haa | 8% | Haa | 9% |
| Calool fadhiga | Haa | 6% | Haa | 5% |
| Matagid | Haa | 6% | Haa | 3% |
| Riyooyin aan caadi ahayn | Haa | 3% | Haa | 1% |
| Cuncun | Haa | 3% | Haa | 3% |
| Cufnaanta caloosha | Haa | 1% | Haa | 3% |
| Dheef-shiidka | Haa | * | Haa | 8% |
| Cilad galmo / libido oo yaraaday | Haa | 20% dheddig / 14% rag ah | Haa | 4% |
| Miisaanka oo yaraada | Maaha | - | Haa | laba% |
Tani ma noqon karto liistada dhameystiran ee waxyeelooyinka xun ee dhici kara. Fadlan tixraac dhakhtarkaaga ama daryeel caafimaad si aad wax badan uga ogaato.
Xigasho: DailyMed ( Trintellix ),, DailyMed ( Prozac )
Isdhexgalka daroogada ee Trintellix iyo Prozac
Trintellix iyo Prozac labadaba waa la shaqeeyaa CYP enzymes beerka. Daawooyinka kale ee saameeya enzymes-kan waxay badali karaan sida Trintellix ama Prozac jirku u shaqeeyo. Qaadashada daroogada midkood CYP2D6 inhibitor sida bupropion ama quinidine waxay sababi kartaa heerar kordhaya ee Trintellix ama Prozac ee jirka. Heerarka daroogada ee kordhay waxay u horseedi karaan halista sii kordheysa ee waxyeelada xun.
Taa bedelkeeda, soo-saareyaasha CYP waxay yareyn karaan heerarka Trintellix ama Prozac ee jirka. Daawooyinka sida carbamazepine iyo phenytoin waxay yareyn karaan waxtarka daawooyinkan niyadjabka ah. Xaaladaha qaarkood, qiyaasaha daawada niyadjabka ayaa laga yaabaa inay u baahdaan in wax laga beddelo marka la qaadanayo daroogooyinka wax soo kiciya ee CYP.
Sababtoo ah Trintellix iyo Prozac waxay kordhiyaan heerarka serotonin ee maskaxda, waa in si taxaddar leh loogu adeegsadaa daroogooyinka kale ee u shaqeeya si isku mid ah. Daawooyinka serotonergic sida sertraline, venlafaxine, iyo amitriptyline waxay kordhin karaan halista serotonin syndrome markii lagu qaato Trintellix ama Prozac (eeg Digniinta Trintellix iyo Prozac).
| Daroogada | Fasalka Daroogada | Trintellix | Prozac |
| Bupropion Paroxetine Quinidine | CYP2D6 xakameeyayaasha | Haa | Haa |
| Carbamazepine Phenytoin Rifampin | Soo-saareyaasha CYP | Haa | Haa |
| Phenelzine Selegiline Isocarboxazid | Kahortagayaasha Monoamine oxidase (MAOIs) | Haa | Haa |
| Sertraline Paroxetine Duloxetine Mirtazapine Venlafaxine Amitriptyline Desipramine Tramadol Fentanyl Lithium Buspirone Trazodone John's Wort | Dawooyinka Serotonergic | Haa | Haa |
| NSAIDs Aspirin Warfarin | Daawooyinka farageliya xinjirowga dhiigga | Haa | Haa |
* La tasho xirfadle daryeel caafimaad isdhexgalka kale ee daroogada.
Digniinta Trintellix iyo Prozac
Isticmaalidda dawooyinka lidka diiqadda waxay kordhin kartaa halista fikradaha isdilka ah ee dadka qaarkood, gaar ahaan dhalinyarada waaweyn iyo carruurta. Waxaa muhiim ah in lala socdo saameyntan xun isla markaana la raadsado talo caafimaad haddii ay soo baxaan.
Qaadashada Trintellix ama Prozac oo ay la socdaan dawooyinka lidka ku ah diiqadda ee kale ayaa sababi kara cilladda serotonin , xaalad halis ah oo suuragal ah in loo dhinto. Qaar ka mid ah opioids sida fentanyl iyo tramadol ayaa sidoo kale kordhin kara halista cudurka serotonin syndrome. Calaamadaha cudurka 'serotonin syndrome' waxaa ka mid noqon kara qandho sare, kacsanaan, gariir, ardayda la ballaadhiyo, iyo shuban. Haddii aad isku aragto mid ka mid ah astaamahan, raadi daryeel caafimaad oo degdeg ah.
Qaadashada Trintellix ama Prozac oo leh dhiig khafiifiyeyaal sida asbiriin iyo warfarin waxay kordhin kartaa halista dhiig-baxa. Qaadashada daawooyinkan waxay sababi kartaa dhiig bax aan caadi ahayn iyo boogaha caloosha.
Trintellix iyo Prozac waxay sababi karaan hyponatremia, ama si aan caadi ahayn oo sodium ah oo dhiigga ku jirta. Hyponatremia waxaa badanaa lala xiriiriyaa cilladda hormoonka aan fiicnayn ee loo yaqaan 'antidiuretic hormone' (SIADH).
Trintellix iyo Prozac waxay kordhin karaan halista glaucoma, ama si aan caadi ahayn oo u hooseeya cadaadiska dhiigga ee isha. Glaucoma waxay u horseedi kartaa dhaawac dareemayaasha indhaha iyo indho la'aan haddii aan la daaweyn.
Prozac wuxuu kaloo saameyn ku yeelan karaa garaaca wadnaha. Qaadashada Prozac waxay kordhin kartaa halista wadna garaac aan caadi ahayn gaar ahaan kuwa horay u soo maray dhibaatooyinka wadnaha ama arrhythmias.
Su'aalaha badanaa la isweydiiyo ee ku saabsan Trintellix iyo Prozac
Waa maxay Trintellix?
Trintellix (vortioxetine) waa mid ka-hortagga niyadjabka ah ee loo yaqaan 'FDA-ansixiyay' 2013-ka ee loogu talagalay daaweynta xanuunka weyn ee niyadjabka. Waxaa badanaa loo qaataa 10 mg oo kiniin ah hal mar maalintii ama iyadoo aan la cunin. Trintellex hadda waxaa loo oggol yahay isticmaalka dadka waaweyn oo keliya.
Waa maxay Prozac?
Prozac waa daawada lidka ku ah diiqadda ee loo yaqaan 'SSRI antidepressant' oo loo isticmaalo in lagu daaweeyo cillad weyn oo niyad jab ah. Waxaa sidoo kale loo isticmaali karaa in lagu daaweeyo cudurada kale ee caafimaadka maskaxda sida OCD, jahwareerka argagaxa, iyo bulimia. Prozac waxaa badanaa loo qaataa kiniin dhan 20 mg hal mar maalintii diiqadda.
Trintellix iyo Prozac ma isku mid baa? / Maxaa ka dhigaya Trintellix mid ka duwan?
Maya. Trintellix iyo Prozac isku mid ma aha. Trintellix waa daawo magac cusub ku cusub oo keliya oo la oggol yahay in lagu daweeyo murugada dadka waaweyn. Prozac waxaa loo heli karaa magac caan ah ama daawo guud oo loo isticmaali karo in lagu daaweeyo niyad-jabka dadka waaweyn iyo carruurta 8 sano iyo ka weyn ah.
Ma Trintellix ama Prozac ayaa ka fiican?
Xilligan, ma jiraan tijaabooyin caafimaad oo madax-ilaa-madax ah oo isbarbar dhigaya Trintellix iyo Prozac. Si kastaba ha noqotee, labadaba daawooyinka dhakhtarku qoro waxay waxtar u leeyihiin yareynta calaamadaha niyadjabka. Iyada oo kuxiran xaaladdaada guud, dhakhtarkaagu wuxuu kuu qori karaa mid kale.
Ma isticmaali karaa Trintellix ama Prozac inta aan uurka leeyahay?
Trintellix ama Prozac waa in la isticmaalo oo keliya xilliga uurka haddii waxtarradu ka culus yihiin halista. Qaadashada Trintellix ama Prozac inta lagu jiro uurka waxay kordhin kartaa halista cilladaha dhalashada. La hadal dhakhtarkaaga haddii aad uur leedahay ama aad naas nuujiso ka hor intaadan qaadan daawadahan niyadjabka.
Ma ku isticmaali karaa Trintellix ama Prozac aalkolo?
Guud ahaan laguma talin in la isticmaalo khamriga lidka diiqadda. Qaadashada Trintellix ama Prozac inta aad cabayso aalkolo waxay kordhin kartaa halista waxyeellooyinka xun sida dawakhaad iyo lulmo.
Mudo intee le'eg ayey ku qaadaneysaa Trintellix inuu shaqo bilaabo?
Sida dawooyinka lidka ku ah diiqadaha kale, Trintellix si dhakhso leh uma bilaabo shaqada. In kasta oo ay qaadan karto 2 toddobaad in la bilaabo dareemidda faa'iidooyinka Trintellix, waxay inta badan qaadan kartaa 4 toddobaad ama ka badan in la dareemo saamaynta buuxda ee daroogada.
Waa maxay waxyeelooyinka Trintellix?
Dhibaatooyinka ugu badan ee loo yaqaan 'Trintellix' waa lallabbo, matag, iyo calool istaag. Dhibaatooyinka kale ee caadiga ah ee Trintellix waxaa ka mid ah af qalalan iyo dawakhaad.
Trintellix miyuu kaa caawiyaa diiradda?
Trintellix waxay si dadban uga caawin kartaa diiradda. Waxaa ugu horreyn loo isticmaalaa in lagu daaweeyo astaamaha niyad-jabka oo ay ku jiri karaan daal, isbeddel ku yimaada rabitaanka cuntada, iyo dhibaatooyin xagga feejignaanta ama diiradda Adoo kor u qaadaya heerarka serotonin iyo yareynta calaamadaha niyadjabka, Trintellix ayaa laga yaabaa inay ka caawiso diiradda.
