Ugu Weyn Ee >> Daroogada Vs. Saaxiib >> Ku dhiiri geli Ellipta iyo Spiriva: Kala duwanaanshaha, isku ekaanshaha, iyo adiga yaa kuu fiican

Ku dhiiri geli Ellipta iyo Spiriva: Kala duwanaanshaha, isku ekaanshaha, iyo adiga yaa kuu fiican

Daroogada Vs. Saaxiib

Sida laga soo xigtay Ururka Sambabka Mareykanka , Cudurka sambabaha ee joogtada ah, ama COPD, ayaa ah sababta seddexaad ee ugu sareysa ee dhimashada cudurada Mareykanka In ka badan 16 milyan oo qof ayaa laga helay COPD, iyadoo malaayiin dad ah ay u badan tahay inay ku dhacday laakiin aan wali laga warqabin COPD waa cudur sanbabada oo bararsan. Bukaannada qaba COPD badanaa waxay la kulmaan dhibaato neefsasho, qufac, xiiq, iyo soo saar xab. COPD waxaa ku jira emphysema iyo boronkiitada raaga. Laba daawo oo caadi ah oo loo isticmaalo in lagu maareeyo COPD waa daawooyin afka laga neefsado oo la yiraahdo Incruse Ellipta iyo Spiriva.

Incruse Ellipta iyo Spiriva labaduba waa dawooyin magac magac kuyaal oo loogu talagalay daaweynta muddada dheer ee dayactirka COPD . Labada daawoba waxaa ansixiyay Maamulka Cuntada iyo Dawooyinka ee Mareykanka (FDA). Waxaa lagu kala soocay koox daawo ah oo loo yaqaan 'anticholinergics'. Waxay ku shaqeeyaan nasinta muruqyada sanbabada, taasoo ka dhigaysa neefsashada mid fudud.

In kasta oo Incruse Ellipta iyo Spiriva ay labaduba yihiin dawooyinka lidka ku ah dawooyinka loo isticmaalo 'COPD', haddana si sax ah iskumid ma aha. Sii wad aqrinta hoose si aad waxbadan uga ogaato daawo kasta.

Maxay yihiin farqiga ugu weyn ee u dhexeeya Incruse Ellipta iyo Spiriva?

Incruse Ellipta iyo Spiriva labaduba waa daawooyinka xinjirowga lidka ku ah, ee lagu heli karo kaliya magaca magaca. Waxaa sidoo kale looyaqaanaa antagonistayaasha muscarinic muddada-dheer (LAMA).

Magaca kiimikada ee Incruse Ellipta waa umeclidinium. Waxaa lagu heli karaa foomka neefta keliya. GlaxoSmithKline (GSK) waxay sameysaa Incruse Ellipta.

Magaca kiimikada ee Spiriva waa tiotropium bromide. Waxaa loo heli karaa labadaba kaabsal afka ah (neefta oo afka laga qaato, oo aan la liqin - sidoo kale loo yaqaan qallaji budada qalalan) iyo ceeriga neefta oo afka laga qaato. Boehringer Ingelheim Pharmaceuticals wuxuu sameeyaa Spiriva.

Farqiga ugu weyn ee u dhexeeya Incruse Ellipta iyo Spiriva
	Ku darso Ellipta	Spiriva
Fasalka daroogada	Anticholinergic	Anticholinergic
Summad / astaan guud	Summad	Summad
Waa maxay magaca guud?	Umeclidinium	Bromide Tiotropium
Waa noocee (yada) daroogadu soo gasho?	Ku dheji Ellipta Inhaler (budada neefta)	Spiriva Handihaler (kaabsaska neefsashada), Spiriva Respimat (ceeriga neefta)
Waa maxay qiyaasta caadiga ah?	Hal neefsi oo afka ah (62.5 mcg) hal mar maalintii isku waqti maalin kasta	Spiriva Handihaler: Laba neef oo afka laga qaato oo ka kooban budada ku jirta hal kaabsal oo ah Spiriva (18 mcg) hal mar maalintii, aaladda Handihaler (kaabsoosha waxaa loogu talagalay in lagu neefsado oo keliya afka, mana aha in la liqo) Spiriva Respimat: 2 neefta oo afka laga qaato (oo ah 1.25 mcg ama 2.5 mcg) hal mar maalintii
Muddo intee le'eg ayaa daaweynta caadiga ah?	Muddo-dheer	Muddo-dheer
Ayaa si caadi ah u isticmaala daawada?	Dadka waaweyn	Handihaler: Dadka waaweyn Aruurinta: Dadka waaweyn iyo carruurta jirta lix sano iyo wixii ka weyn

Xaaladaha ay daweeyaan Incruse Ellipta iyo Spiriva

Incruse Ellipta iyo Spiriva waxaa loogu talagalay daaweynta dayactirka cudurada sambabada ee joogtada ah (COPD). Si qaas ah, macluumaadka soo saaraha Spiriva Handihaler wuxuu xusayaa in loo isticmaalo in lagu yareeyo sii xumeynta bukaanada COPD.

Spiriva Respimat waxay leedahay hal tilmaan oo dheeri ah — daaweynta dayactirka cudurka neefta ee bukaanka jira 6 sano iyo wixii ka weyn.

Midkoodna daroogada looma isticmaali karo weerar daran.

Xaaladda	Ku darso Ellipta	Spiriva
Daaweynta dayactirka ee COPD	Haa	Haa (Handihaler iyo Respimat)
Daaweynta neefta ee bukaanka jira lix sano iyo wixii ka weyn	Maaha	Haa (Jawaab)

Incruse Ellipta ama Spiriva waxtar badan ma leedahay?

Waxaa jira xog yar oo isbarbar dhiga labada daroogo si toos ah. A 12-toddobaad daraasad marka la barbar dhigo waxtarka iyo badbaadada Incruse Ellipta iyo Spiriva in ka badan 1,000 bukaan oo qaba COPD. Dhamaadka ugu dambeeya wuxuu ahaa qulqulka qasabka ah ee hal ilbiriqsi (oo sidoo kale loo yaqaan FEV1) maalintii 85. Bukaannada waxaa lagu qiimeeyay iyadoo la adeegsanayo Su'aalaha Neefsashada ee St George iyo qiimeyno kale. Labada daroogoba waxay muujiyeen horumar macno leh oo xagga nolosha ah waana loo dulqaatay xagga nabadgelyada. Daraasadu waxay soo gabagabeysay Incruse Ellipta inay ka waxtar badan tahay Spiriva.

Kaliya bixiyahaaga daryeelka caafimaadka ayaa go'aamin kara daawada kuugu waxtarka badan adiga. Isaga ama iyadu waxay tixgelin karaan darnaanta astaamahaaga iyo taariikhdaada caafimaad, iyo dawooyinka kale ee aad qaadato ee suurtagal noqon kara inay la falgalaan Incruse Ellipta ama Spiriva.

Daboolida iyo qiimaha isbarbar dhiga Incruse Ellipta iyo Spiriva

Qorshayaasha caymiska iyo Medicare Qaybta D ayaa daboolaya Incruse Ellipta iyo Spiriva, laakiin qaddarka caymiska ayaa ku kala duwan qorshaha.

Qiimaha jeebka lagala baxo ee ah 'Incruse Ellipta inhaler' waa qiyaastii $ 477, laakiin waxaad isticmaali kartaa kaarka 'SingleCare' si aad hoos ugu dhigto qiimaha illaa $ 306.

Qiimaha jeebka ee Spiriva Handihaler waa qiyaastii $ 634, iyo Spiriva Respimat waa ilaa $ 600. Isticmaalka tigidhka 'SingleCare coupon' wuxuu hoos u dhigi doonaa qiimaha illaa $ 404 Handihaler ama Respimat midkood.

	Ku darso Ellipta	Spiriva
Caadi ahaan caymiska ayaa daboolaya?	Haa	Haa
Caadi ahaan waxaa daboola Medicare Qaybta D?	Haa	Haa
Qiyaasta caadiga ah	1 neefsasho	1 Handihaler ama 1 Jawaab
Bixinta lacagta caadiga ah ee 'Medicare'	$ 8- $ 395	$ 3- $ 524
Qiimaha SingleCare	$ 306 +	$ 404 +

Waxyeelooyinka guud ee Incruse Ellipta iyo Spiriva

Saameynaha ugu caansan ee loo yaqaan 'Incruse Ellipta' waa nasopharyngitis (hargab caadi ah), infekshinka mareenka sare, iyo qufac.

Dhibaatooyinka ugu badan ee Spiriva waa infekshinka sare ee neef mareenka, sinusitis, laab xanuun, afka oo qallalan, calool istaag, iyo infekshinka kaadi mareenka.

Tani ma aha liistada dhammaystiran ee waxyeellooyinka soo raaca. Dhibaatooyinka kale ee xun ayaa dhici kara. La xiriir dhakhtarkaaga si aad u hesho liis dhan oo ah dhibaatooyinka soo raaca ee Incruse Ellipta iyo Spiriva.

	Ku darso Ellipta	Spiriva
Waxyeellada	Ma khuseysaa?	Joogtaynta	Ma khuseysaa?	Joogtaynta
Nasopharyngitis / pharyngitis	Haa	8%	Haa	9%
Cudurka marinka neef mareenka sare	Haa	5%	Haa	41%
Qufac	Haa	3%	Haa	> 3%
Laab xanuun	Maaha	-	Haa	7%
Af qalalan	Maaha	-	Haa	16%
Calool fadhiga	Maaha	-	Haa	4%
Matagid	Maaha	-	Haa	4%
Sinusitis	Haa	Lama sheegin	Haa	kow iyo toban%
Firiiric	Haa	Lama sheegin	Haa	4%
Arthralgia (xanuun wadajir ah)	Haa	laba%	Haa	4.2%
Caabuqa kaadi mareenka	Haa	Lama sheegin	Haa	7%

Xigasho: DailyMed ( Ku darso Ellipta ), DailyMed ( Spiriva )

Isdhexgalka daroogada ee Incruse Ellipta iyo Spiriva

Sababtoo ah Incruse Ellipta iyo Spiriva waa daawooyinka xinjirowga lidka ku ah, waa inaan loo isticmaalin daawooyinka kale ee xinjirowga lidka ku ah. Isku-darka ayaa sababi kara kororka dhibaatooyinka soo raaca, sida kaadi-haynta kaadi-haynta ama glaucoma-cidhifka-adag.

Isdhexgalka kale ee daroogada ayaa dhici kara. La tasho daryeel caafimaad bixiyahaaga liiska buuxa ee isdhexgalka daroogada.

Daroogada	Fasalka daroogada	Ku darso Ellipta	Spiriva
Alloonnada Belladonna Benztropine Clidinium Darifenacin Dicyclomine Diphenhydramine Hyoscyamine Ipratropium Orphenadrine Oxybutynin Skopolamine Solifenacin Tolterodine Trihexyphenidyl	Dawooyinka Anticholinergics	Haa	Haa

Digniinta Incruse Ellipta iyo Spiriva

Ha u isticmaalin Incruse Ellipta ama Spiriva haddii aad u nuglaato xasaasiyad weyn oo ku saabsan borotiinka caanaha ama wax ka mid ah maaddooyinka.
Dhiirrigelinta Ellipta ama Spiriva looguma talagalin in loo isticmaalo xaaladaha degdegga ah ee sii xumaanaya ama khatarta ku ah nolosha ee COPD. Daawooyinkan laguma baranin dhacdooyin ba'an waana inaan loo isticmaalin in lagu yareeyo astaamaha daran. Ha u qaadin qaadasho dheeraad ah gargaarka astaamaha daran. Bixiyaha xanaanada caafimaadkaaga waa inuu ku siiyaa tilmaamo ku saabsan maareynta xaalad deg deg ah - waxaad u badan tahay inaad u isticmaasho neefsasho wax ku qabata oo gaagaaban.
Dhiirrigelinta Ellipta ama Spiriva waxay sababi kartaa xaalad halis ah oo naf-gooyada ah oo ku saabsan bronchospasm (ka sii darista neefsashada ama xiiqda), taas oo isla markaaba lagu daaweeyo neef-qabatin gaaban oo shaqeynaya Haddii tani dhacdo, jooji Incruse Ellipta ama Spiriva isla markiiba. Bixiyahaaga daryeelka caafimaad ayaa kuu qori kara daaweyn kale.
Dhiirrigelinta Ellipta ama Spiriva waxay sababi karaan xasaasiyad xasaasiyadeed, oo ay ku jiraan anaphylaxis, angioedema, cuncun, ama finan. Jooji Dhiirrigelinta Ellipta ama Spiriva oo la xiriir bixiyahaaga daryeelka caafimaadka haddii mid ka mid ah dareen-celintaas ay dhacdo. Haddii aad dhib ku qabtid neefsashada ama aad isku aragto barar bushimahaaga, carrabkaaga, iyo afkaaga, raadi daaweyn caafimaad oo degdeg ah.
U isticmaal Incruse Ellipta ama Spiriva taxaddar bukaanka qaba glaucoma-xagasha cidhiidhiga ah. Bukaanka iyo qorayaashoodu waa inay fiiriyaan astaamaha glaucoma-cagaarshowga daran (isha xanuun, araga araga, araga indhaha). La tasho daryeel caafimaad bixiyahaaga isla markiiba haddii mid ka mid ah astaamahan ay dhacaan.
U isticmaal Incruse Ellipta ama Spiriva taxaddar bukaanada leh kaadi haysta. Bukaanka iyo kuwa wax qoraya waa inay ka feejignaadaan astaamaha haynta kaadida, sida kaadida oo xanuun leh iyo kaadi la'aantu. La tasho bixiyahaaga daryeelka caafimaadka isla markiiba haddii aad isku aragto astaamahan.

Spiriva kaliya:

La soco bukaanada qaba cillad dhexdhexaad ah ama daran oo xagga kelyaha ah oo loogu talagalay saamaynta daawada xinjirowga lidka ku ah.
Kaabsoosha waxaa loogu talagalay oo keliya in lagu neefsado afka mana aha in la liqo. Kaliya ku isticmaal aaladda Handihaler.

Su'aalaha badanaa la isweydiiyo ee ku saabsan Incruse Ellipta iyo Spiriva

Waa maxay Incruse Ellipta?

Incruse Ellipta waa daawada lidka ku ah dawada dawada lidka ku ah dawada dawada loo qaato ee loo isticmaalo COPD. Waxay kaa caawinaysaa inaad dabciso sambabaha, neefta oo fudud.

Waa maxay Spiriva?

Spiriva sidoo kale waa daawada lidka ku ah dawada lidka ku ah dawada xinjirowga lidka ku ah ee loo isticmaalo COPD. Waxaa loo heli karaa sidii kaabsal la neefsaday iyo sidoo kale ceeryaamo la neefsado.

Incruse Ellipta iyo Spiriva ma isku mid baa?

Labada daawoba waa isku mid waana isku nooc daawooyin. Si kastaba ha noqotee, waxay leeyihiin xoogaa khilaafaad ah, sida waxyeellooyinka iyo qiyaasta, ee kor lagu soo sheegay.

Ma Incruse Ellipta ama Spiriva ayaa ka fiican?

Xog xaddidan ayaa la heli karaa marka la barbardhigo Incruse Ellipta iyo Spiriva. Hal daraasad ayaa muujisay Incruse Ellipta inay waxtar badan leedahay, laakiin labada daawoba inay si isku mid ah u badbaadaan. Bixiyahaaga daryeelka caafimaadka ayaa go'aamin kara daawada adiga kuufiican.

Ma isticmaali karaa Incruse Ellipta ama Spiriva inta aan uurka leeyahay?

Ma jiro macluumaad ku filan oo ku saabsan saameynta Incruse Ellipta ama Spiriva uurka. La tasho OB-GYN-kaaga wixii talo caafimaad ah. Haddii aad horey u qaadaneysid Incruse Ellipta ama Spiriva oo aad ogaatid inaad uur leedahay, la tasho OB-GYN-gaaga.

Miyaan ku isticmaali karaa Incruse Ellipta ama Spiriva aalkolo?

In kasta oo Incruse Ellipta ama Spiriva aysan la falgalin aalkolada, cabitaanka aalkolada muddo dheer waxay kordhin kartaa astaamaha COPD waxayna daciifin kartaa nidaamkaaga difaaca, taasoo ka sii dareysa calaamadahaaga COPD. La tasho daryeel caafimaad bixiyahaaga wixii macluumaad dheeraad ah ee ku saabsan aalkolada iyo COPD.

Ma Incruse Ellipta waa steroid?

Maya. Ku dhiiri geli Ellipta maahan steroid. Waxaa loo qoondeeyey inay tahay daawo xinjirowga lidka ku ah. Waxay dejisaa muruqyada marinnada hawada si neefsashadu u fududaato.

Neefsashada qaarkood waxay ka kooban yihiin corticosteroid la neefsaday oo loo isticmaalo daaweynta COPD. Advair wuxuu ka kooban yahay fluticasone (steroid) iyo salmeterol (beta-agonist oo waxqabad dheer). Tusaalaha kale waa Breo Ellipta, oo ay kujiraan fluticasone furoate (steroid) iyo vilanterol (beta-agonist muddo dheer shaqeynayay).

Neefsashada u dhiganta Spiriva?

Neefsashada kale ee isla qaybta Spiriva iyo Incruse Ellipta waxaa ka mid ah Tudorza Pressair (aclidinium) iyo Seebri Neohaler (glycopyrrolate).

Waa maxay daawada neefta ugu fiican ee COPD?

Taasi waa su’aal adag. Waxay kuxirantahay dhowr arimood, sida darnaanta iyo nooca astaamaha, taariikhdaada caafimaad, iyo daawooyinka kale ee aad qaadato. Bixiyahaaga daryeel caafimaad ayaa go'aamin kara daawada neefta kuu roon ee adiga kugu habboon.

Waxaa jira daraasiin daawooyin neef ah oo suuqa kujira. Waa kuwan daaweynno badan oo sida caadiga ah loo nuugo oo loogu talagalay COPD:

SABA (waxqabadka gaaban ee bronchodilatore, ama beta-agonists-gaaban): Albuterol HFA, Proair HFA, Proventil HFA, Ventolin HFA, Xopenex

LABAs (muddo dheer shaqeynayay beta2 agonists): Brovana (arformoterol), Serevent (salmeterol)

LAMAs (antagonistayaasha muscarinic muddada-dheer): Ku dheji Ellipta (umeclidinium), Seebri (glycopyrrolate), Spiriva (tiotropium) Respimat ama Handihaler, Tudorza Pressair (aclidinium)

LAMA + LABA qalabka neefsashada: Anoro Ellipta (umeclidinium / vilanterol), Bevespi Aerosphere (glycopyrrolate / formoterol), Stiolto Respimat (olodaterol / tiotropium),

Utibron Neohaler (indacaterol / glycopyrrolate)

Corticosteroids la neefsaday: Qvar RediHaler (beclomethasone), Pulmicort Flexhaler (budesonide)

Isku darka corticosteroid + LABA: Symbicort (budesonide / formoterol), Advair (fluticasone / salmeterol), Breo (fluticasone / vilanterol), Dulera (mometasone / formoterol)