Pantoprazole iyo omeprazole: Kala duwanaanshaha, isku ekaanshaha, iyo yaa adiga kuu fiican
Daroogada Vs. SaaxiibDulmarka daroogada & kala duwanaanshaha ugu weyn | Xaaladaha la daweeyay | Wax ku oolnimada | Caymiska caymiska iyo isbarbardhiga qiimaha | Dhibaatooyinka ay keento | Isdhexgalka daroogada | Digniinta | Su'aalaha
Pantoprazole iyo omeprazole waa laba proton pump inhibitors (PPIs) oo loo isticmaalo daaweynta xaaladaha dheefshiidka. Labada daroogoba waxaa loo isticmaali karaa cudurka 'gastroesophageal reflux disease' (GERD), oo ah qaab xanuun daran oo soo noqnoqda, iyo hunguriga hunguriga. Waxay ku shaqeeyaan yareynta dheecaanka aashitada ee caloosha. In kasta oo pantoprazole iyo omeprazole ay yihiin daawooyin isku mid ah, haddana waxay leeyihiin kala duwanaan xoogaa ah.
Maxay ku kala duwan yihiin pantoprazole iyo omeprazole?
Pantoprazole (Kuubannada Pantoprazole) waa magaca guud ee loo yaqaan 'Protonix' waxaana hadda lagu iibsadaa warqad dhakhtar oo keliya. Waa FDA-ogolaatay in lagu daaweeyo GERD dadka waaweyn iyo carruurta da'doodu tahay 5 sano iyo wixii ka weyn muddo caadi ah illaa 8 toddobaad. Pantoprazole (faahfaahin dheeraad ah oo ku saabsan Pantoprazole) waxaa loo bixiyaa sidii kiniin daahin-sii-deyn ah ama ganaax dareere ah. Waxaa sidoo kale loo qaadan karaa iyada oo ah cirbadeynta xididka (IV) ee isbitaal ama rug caafimaad.
Omeprazole (Kuuboonada Omeprazole) sidoo kale waxaa loo yaqaanaa magaceeda, Prilosec, waxaana lagu iibsan karaa warqad dhakhtar qoro ama miiska lagu iibsado. Waxay u shaqeysaa si la mid ah pantoprazole sida PPI. Si kastaba ha noqotee, waxaa sidoo kale loo oggol yahay FDA in lagu daaweeyo boogaha duodenal, infekshinka 'helicobacter pylori' (H. pylori), iyo boogaha caloosha ku jira ee lagu daro GERD iyo hunguriga hunguriga. Omeprazole (faahfaahin dheeraad ah oo Omeprazole ah) ayaa daaweyn kara GERD ee dadka waaweyn iyo carruurta jirta 1 sano iyo ka weyn. Waxay u timaadaa sidii kaabsul-dib-u-sii-daayay, kiniin, iyo hakin dareere ah.
| Farqiga ugu weyn ee u dhexeeya pantoprazole iyo omeprazole | ||
|---|---|---|
| Pantoprazole | Omeprazole | |
| Fasalka daroogada | Proton pump inhibitor (PPI) | Proton pump inhibitor (PPI) |
| Summad / astaan guud | Nooca guud ayaa la heli karaa | Nooca guud ayaa la heli karaa |
| Waa maxay magaca guud? Waa maxay magaca sumaddu? | Pantoprazole Protonix | Omeprazole Prilosec |
| Waa noocee (yada) daroogadu soo gasho? | Kiniin afka ah, daahitaan-sii-deyn Hakinta afka Cirbadeynta IV / faleebo | Kiniin afka ah, daahitaan-sii-deyn Kaabsal afka ah, dib-u-sii-daayay Hakinta afka Cirbadeynta IV / faleebo |
| Waa maxay qiyaasta caadiga ah? | 40 mg hal mar maalintii | 20 mg hal mar maalintii |
| Muddo intee le'eg ayaa daaweynta caadiga ah? | Ilaa 8 toddobaad | 4 ilaa 8 toddobaad |
| Ayaa si caadi ah u isticmaala daawada? | Dadka waaweyn iyo carruurta jirta 5 sano iyo wixii ka weyn | Dadka waaweyn iyo carruurta jirta 1 sano iyo wixii ka weyn |
Xaaladaha lagu daaweeyo pantoprazole iyo omeprazole
Pantoprazole iyo omeprazole labaduba waa FDA loo oggolaaday in lagu daaweeyo astaamaha laabjeexa ee ka yimaada GERD iyo hunguriga hunguriga. PPI-yada sida pantoprazole iyo omeprazole ayaa ka awood badan antacids-ka caadiga ah, sida xanibaadayaasha histamine (H2). Badanaa waa loo qoraa daaweynta muddada-gaaban aan soconayn wax ka badan 8 toddobaad.
Pantoprazole iyo omeprazole waxay sidoo kale daaweyn karaan xaaladaha sirta ah ee sababa caloosha inay soo saarto aashito badan oo caloosha ku jirta. Cudurka 'Zollinger-Ellison syndrome' waa xaalad sababi karta hidde-wadayaasha aashitada waxayna ku lug leedahay burooyin ku dhaca ganaca ama duodenum (qaybta koowaad ee xiidmaha yar).
Pantoprazole iyo omeprazole ayaa sidoo kale kaa caawin kara daaweynta xaaladaha kale sida boogaha duodenal, boogaha caloosha ama caloosha, iyo boogaha caloosha. Boogahaas waxaa badanaa keena infakshan ka yimaada bakteeriyada loo yaqaan H. pylori. Halka omeprazole loo oggol yahay inuu daaweeyo H. pylori oo ay weheliso dawooyin kale, pantoprazole waxaa loo isticmaalaa calaamadda infekshankan sidoo kale.
Isticmaalka kale ee calaamada ka baxsan ee labada daawooyinba waxaa ka mid ah hunguriga Barrett iyo boogaha ka soo baxa isticmaalka daawooyinka anti-bararka ee nonsteroidal (NSAIDs).
| Xaaladda | Pantoprazole | Omeprazole |
| Cudurka Qaaxada ee 'Gastroesophageal Reflux Disease' (GERD) | Haa | Haa |
| Erosif Esophagitis | Haa | Haa |
| Cudurka 'Zollinger-Ellison syndrome' | Haa | Haa |
| Xaaladaha sirta ah | Haa | Haa |
| Boogaha Duodenal | Off-calaamadda | Haa |
| Boogaha caloosha | Off-calaamadda | Haa |
| Xanuunka H. Pylori | Off-calaamadda | Haa |
| Hunguriga Barrett | Off-calaamadda | Off-calaamadda |
| Dheef-shiidka | Off-calaamadda | Off-calaamadda |
| Nabarrada NSAID | Off-calaamadda | Off-calaamadda |
| Boogaha Peptic | Off-calaamadda | Off-calaamadda |
Ma dooneysaa qiimaha ugu fiican ee Omeprazole?
Saxiix ogeysiisyada qiimaha Omeprazole oo ogow goorta sicirka isbeddelo!
Hel digniinta qiimaha
Pantoprazole ama omeprazole waxtar badan ma leeyahay?
Pantoprazole iyo omeprazole ayaa la muujiyay inay wax ku ool u yihiin daaweynta GERD. Gudaha falanqaynta meta oo uruuriyay 40 daraasadood oo kaladuwan, natiijooyinka lama helin kala duwanaansho weyn oo ku saabsan waxtarka udhaxeeya PPIs. Pantoprazole waxaa lagu ogaadey inuu si siman waxtar ugu leeyahay omeprazole. Qaar ka mid ah tijaabooyinka bukaan-eegtada laba-indha-la'aanta ah ayaa sidoo kale ku jiray PPI-yada kale sida Nexium (esomeprazole) , lansoprazole (Prevacid), iyo rabeprazole (Aciphex).
Mid barasho oo lagu soo daray falanqaynta maadada ayaa lagu ogaaday in pantoprazole uu ka waxtar badan yahay omeprazole daaweynta boogaha caloosha. Natiijooyinka waxaa laga soo ururiyay 5 daraasadood oo ku saabsan waxtarka ku saleysan dib-u-eegista ee heerarka bogsashada. In kasta oo pantoprazole la ogaaday inay waxtar badan leedahay, waxaa laga yaabaa inay jiraan cilladaha leh qiyaasta daawada oo aan sinnayn.
Pantoprazole iyo omeprazole labaduba waa daawooyin isbarbar dhigi kara marka loo eego waxtarka. Mid ayaa laga doorbidi karaa kan kale iyadoo kuxiran xaalada la daaweynayo iyo qiimaha daawada. La tasho dhakhtar si aad u go'aamiso midka PPI way fiicnaan kartaa adiga.
Daboolida iyo isbarbar dhiga qiimaha pantoprazole iyo omeprazole
Pantoprazole waa daawo guud oo badanaa laga helo Medicare iyo qorshooyinka caymiska badankood. Celceliska qiimaha tafaariiqda ee pantoprazole waa kudhowaad $ 522. Waxaa laga yaabaa inaad awoodo inaad waxbadan ku keydiso kuuboon SingleCare ah oo hoos ugu dhigi kara qiimaha $ 28.
Soo qaado kaarka dhimista ee SingleCare
Omeprazole waa daawo guud oo badanaa laga helo Medicare iyo qorshooyinka caymiska badankood. Celceliska qiimaha tafaariiqda ee omeprazole waa kudhowaad $ 67.99. Kuuboonada 'SingleCare' waxaad ku filan kartaa inaad ku bixiso $ 9-20 30, kaabsal 20mg.
| Pantoprazole | Omeprazole | |
| Caadi ahaan caymiska ayaa daboolaya? | Haa | Haa |
| Caadi ahaan waxaa daboolaya Medicare? | Haa | Haa |
| Qiyaasta caadiga ah | 40 mg (tirada 30) | 20 mg (tirada 30) |
| Bixinta lacagta caadiga ah ee 'Medicare' | Waxay kuxirantahay qorshahaaga caymiska | Waxay kuxirantahay qorshahaaga caymiska |
| Qiimaha SingleCare | $ 28 | $ 9-20 |
Waxyeelooyinka guud ee pantoprazole iyo omeprazole
Pantoprazole iyo omeprazole waxay sababi karaan waxyeelo sida madax xanuun, dawakhaad, lallabbo, iyo matag. Waxay sidoo kale sababi karaan waxyeelooyin kale oo caloosha ku dhaca sida shuban, calool istaag, calool xanuun ama calool xanuun, iyo qulqul ama gaas. Dhibaatooyinka kale ee la wadaago waxaa ka mid noqon kara xanuunka kalagoysyada, infekshannada neef mareenka sare, iyo asthenia ama tamar la'aan.
Omeprazole sidoo kale wuxuu sababi karaa waxyeelo sida dib u soo celinta aashitada, dhabar xanuun, iyo qufac. Pantoprazole looma baran si loo muujiyo waxyeelooyinkaan gaarka ah sida badanaa.
| Pantoprazole | Omeprazole | |||
| Saamaynta Side | Ma khuseysaa? | Joogtaynta | Ma khuseysaa? | Joogtaynta |
| Madax xanuun | Haa | 12.2% | Haa | 7% |
| Lallabbo | Haa | 7% | Haa | 4% |
| Shuban | Haa | 8.8% | Haa | 4% |
| Calool fadhiga | Haa | <2% | Haa | laba% |
| Calool xanuun | Haa | 6.2% | Haa | 5% |
| Matagid | Haa | 4.3% | Haa | 3% |
| Cufnaanta caloosha | Haa | 3.9% | Haa | 3% |
| Dawakhaad | Haa | 3% | Haa | laba% |
| Xanuun wadajir ah | Haa | 2.8% | Haa | N / A |
| Firiiric | Haa | <2% | Haa | laba% |
| Dib u soo celinta Acid | Maaha | - | Haa | laba% |
| Cudurka marinka neef mareenka sare | Haa | N / A | Haa | laba% |
| Tabar-darri / tamar la’aan | Haa | N / A | Haa | 1% |
| Dhabar xanuun | Maaha | - | Haa | 1% |
| Qufac | Maaha | - | Haa | 1% |
* La tasho dhakhtar ama farmashiistaha wixii waxyeelo ah ee suurtogalka ah.
Xigasho: DailyMed (pantoprazole) , DailyMed (omeprazole)
Isdhexgalka daroogada ee pantoprazole iyo omeprazole
Labada pantoprazole iyo omeprazole labaduba waxay la falgalaan daawooyin isku mid ah. Labadooduba waxay la macaamili karaan daawooyinka antiretroviral-ka sida rilpivirine, atazanavir, iyo saquinavir. Wada qaadashada daawooyinkan waxay wax ka beddeli kartaa waxtarka daawada antiretroviral-ka waxayna kordhin kartaa sunta. Qaadashada pantoprazole ama omeprazole oo leh warfarin waxay kordhin kartaa halista dhiig-baxa. Sidaa darteed, waa in aan la isla qaadan. In kasta oo clopidogrel uusan saameyn ku yeelan karin pantoprazole, waa in laga fogaadaa omeprazole.
Pantoprazole iyo omeprazole waxay la falgalaan daawada methotrexate, daawada antimetabolite, waxayna sababi kartaa halista sunta iyo dhibaatooyinka soo raaca.
Pantoprazole iyo omeprazole looma qaadan karo isla waqtigaas cusbada birta iyo dawooyinka kale ee ku tiirsan aashitada caloosha ee nuugista. Daawooyinka kale ee ku tiirsan aashitada caloosha ee nuugista waxaa ka mid ah daawooyinka kiimiko ah sida erlotinib iyo dasatinib iyo antifungals sida ketoconazole iyo itraconazole.
Sababtoo ah labadaba PPIs ayaa lagu beeray beerka, waxay la falgalaan daawooyin kale oo ay ka baaraandegaan enzymes la mid ah, oo ay ku jiraan enzyme CYP2C19 ah. Si kastaba ha noqotee, sida laga soo xigtay Calaamadda FDA , qaar ka mid ah daawooyinkan, oo ay ku jiraan phenytoin, citalopram, iyo diazepam, lama tusin inay si weyn ula falgalaan pantoprazole. Sidaas oo ay tahay, waa muhiim in lagala hadlo wixii daawooyin ah ee aad la qaadato dhaqtar kahor intaadan qaadanin PPI.
PPIs waxay saameyn ku yeelan karaan natiijooyinka baaritaanka shaybaarada qaarkood. PPIs waxaa lagu yaqaan inay sababo been abuur ah u yihiin baaritaanka kaadida THC.
| Daroogada | Fasalka Daroogada | Pantoprazole | Omeprazole |
| Rilpivirine Nelfinavir Atazanavir Saquinavir Ritonavir | Antiretroviral | Haa | Haa |
| Warfarin | Anticoagulant | Haa | Haa |
| Clopidogrel | Antiplatelet | Maaha | Haa |
| Methotrexate | Antimetabolite | Haa | Haa |
| Mycophenolate mofetil Tacrolimus | Difaaca jirka | Haa | Haa |
| Ketoconazole Itraconazole Voriconazole | Antifungal | Haa | Haa |
| Erlotinib Dasatinib Nilotinib | Dawaynta kimikalka | Haa | Haa |
| Fumarate fuuxan Gluconate fuula Salfateet Ferrous Suugaan Ferrous ah | Cusbada birta ah | Haa | Haa |
| Diazepam Midazolam | Benzodiazepine | Maaha | Haa |
| Phenytoin | Daawaynta suuxdinta | Maaha | Haa |
| Clarithromycin Rifampin | Antibiyootig | Haa | Haa |
| Citalopram | Xakamaynta dawada lidka ku ah serotonin (SSRI) | Maaha | Haa |
| John's Wort | Dhirta | Haa | Haa |
* Tani ma noqon karto liistada dhameystiran ee dhammaan isdhexgalka daroogada ee suurtogalka ah. Takhtarka kala tasho dhammaan daawooyinka aad qaadan karto.
Digniinta pantoprazole iyo omeprazole
Pantoprazole iyo omeprazole laguma talinayo in la isticmaalo muddada-dheer. Isticmaalka muddada-dheer waxaa lala xiriiriyay an halista sii kordheysa ee jabka lafaha . Haddii aad qabtid lafo-beel, waxaad u baahan kartaa inaad kormeerto adeegsiga PPIs.
Xogta qaar ayaa soo jeedisay in dawooyinka PPI ay kordhin karaan halista dhacdooyinka wadnaha iyo wadnaha iyo istaroogga. Si kastaba ha noqotee, FDA iyo kuwa kale warbixinnada xoojinta faa'iidooyinka PPIs ayaa ka culus khatartan.
Sababtoo ah pantoprazole iyo omeprazole ayaa lagu farsameeyaa beerka, waxaa laga yaabaa in lagu hagaajiyo ama laga fogaado kuwa qaba cilladaha beerka.
Pantoprazole iyo omeprazole way ka sii dari karaan ama kordhin karaan halista nidaamka lupus erythematosus, oo ah cudur naadir ah oo isdifaaca jirka.
Daaweynta PPIs waxay kordhin kartaa halista shubanka ee cudurada Clostridium. Khatartani waxay ku sii badnaan kartaa kuwa isbitaalka la dhigo muddo dheer.
Labada pantoprazole iyo omeprazole waxay ku jiraan Uurka Qaybta C waxaana laga yaabaa inay waxyeelo u geystaan ilmaha aan dhalan. La tasho dhakhtar ama daryeel caafimaad haddii aad uur leedahay ama aad naas nuujiso.
Su'aalaha badanaa la isweydiiyo ee ku saabsan pantoprazole iyo Omeprazole
Waa maxay pantoprazole?
Pantoprazole (Protonix) waa daawo proton pump inhibitor (PPI) loo qoro si loogu daaweeyo GERD iyo hunguriga hunguriga. Waxaa badanaa loo qaataa kiniin 40 mg ah oo daaho-sii-deyn ah illaa 8 toddobaad. Waxaa lagu qaadan karaa dadka waaweyn iyo carruurta jirta 5 sano iyo wixii ka weyn.
Waa maxay omeprazole?
Omeprazole (Prilosec) waa daawo PPI loo qoro si loogu daaweeyo GERD iyo hunguriga hunguriga. Sidoo kale waa FDA loo oggolaaday infekshinka H. pylori iyo duodenal ama boogaha caloosha. Waxaa loo qaadan karaa 20 mg oo ah kaabsol dib-u-sii-deyn ah 4 ilaa 8 toddobaad oo dadka waaweyn iyo carruurta ah 1 sano iyo ka weyn.
Pantoprazole iyo omeprazole ma isku midbaa?
Pantoprazole iyo omeprazole waxay ku jiraan isla dawooyin isku nooc ah. Si kastaba ha noqotee, waxay leeyihiin adeegsiyo la ansixiyay oo kala duwan iyo waxyeelooyin. Waxay sidoo kale ku yimaadaan qiyaaso iyo qaabab kala duwan.
Ma pantoprazole ama omeprazole ayaa ka fiican?
Pantoprazole iyo omeprazole labaduba waxtar ayey u leeyihiin GERD iyo hunguriga hunguriga. Hal daawo oo PPI ah ayaa laga doorbidi karaa mida kale iyadoo kuxiran xaalada la daaweynayo iyo qiimaha daawada.
Ma isticmaali karaa pantoprazole ama omeprazole inta aan uurka leeyahay?
Pantoprazole iyo omeprazole laguma talinayo haweenka uurka leh khatarta waxyeelada uurjiifka. Si kastaba ha noqotee, xaaladaha qaarkood, faa'iidooyinka ayaa laga yaabaa inay ka culus yihiin halista. La tasho dhakhtar haddii aad uur leedahay.
Ma ku isticmaali karaa pantoprazole ama omeprazole aalkolo?
Isticmaalka aalkoladu waxay kordhin kartaa waxyeelooyinka qaarkood ee laxiriira pantoprazole ama omeprazole. Sababtoo ah madax xanuunka iyo lallabadu waa waxyeelo caadi ah oo ka timaadda PPIs, dhibaatooyinkaas soo raaca way ka sii dari karaan marka PPIs lagu qaato khamri.
OTC omeprazole ma la mid yahay dawo qorista?
Ka-iibsiga miisaanka badan (OTC) omeprazole wuxuu ka kooban yahay isla daawada iyo xoogga daawada loo qoro omeprazole. OTC omeprazole waxaa loo heli karaa inuu yahay OTC Prilosec oo ah 14-maalin oo la siinayo 20 kiniin oo mg ah. Koorsadan daaweyntu waa in aan la qaadan wax ka badan hal mar 4tii biloodba mar.
Miyaan qaataa Pantoprazole iyo Omeprazole isla waqti isku mid ah?
Pantoprazole iyo omeprazole waa inaan la qaadan isku waqti. Waxay ugu shaqeeyaan qaabab isku mid ah iyagoo xidha wax soo saarka aashitada caloosha ee caloosha. Isku soo wada duuboo waxay kordhin kartaa halista waxyeelada xun.
