Ugu Weyn Ee >> Daroogada Vs. Saaxiib >> Shingrix iyo Zostavax: Kala duwanaanshaha, isku ekaanshaha, iyo yaa adiga kuu fiican

Shingrix iyo Zostavax: Kala duwanaanshaha, isku ekaanshaha, iyo yaa adiga kuu fiican

Daroogada Vs. Saaxiib

Hadda waxaa jira laba tallaal oo la bixin karo si looga hortago herpes zoster, oo badanaa loo yaqaan shingles: Shingrix iyo Zostavax. Tallaalka shingles waxaa lagula talinayaa dadka waaweyn markay gaaraan 50 jir.

Dadka badankood wuxuu ku dhacay fayraska 'varicella zoster virus' haddii ay weligoodba ku dhacaan busbus. Ka dib markii busbusku xalliyo, fayraska 'varicella zoster virus' wuxuu jiifaa jirka muddo sanado ah, haddii uusan weligiis ahayn. Goor dambe oo nolosha ah, fayrasku wuxuu dib u hawlgelin karaa sida shingles wuxuuna sababi karaa finan daran oo inta badan ku wareegsan wajiga ama jirkaba.

In kasta oo Shingrix iyo Zostavax ay ku shaqeeyaan siyaabo isku mid ah si looga hortago shingles, haddana waxaa jira faraqyo muhiim ah oo u dhexeeya labadaas.

Maxay yihiin farqiga u dhexeeya Shingrix iyo Zostavax?

Shingrix (Waa maxay Shingrix?) Waa recombinant, tallaalka zoster adjuvanted oo markii ugu horreysay la ansixiyay FDA 2017. Waxay isticmaashaa varicella-zoster glycoprotein E antigen si ay u soo saarto jawaab celin jirka ah. Wax lagu daro, ama qayb lagu daray, ayaa gacan ka geysata kor u qaadista ka-hortagga jirka ee fayraska. Sababtoo ah Shingrix waa tallaal aan firfircooneyn, waxaa loo isticmaali karaa bukaannada difaaca jirka ama kuwa difaaca jirkoodu daciifka yahay.

Shingrix waxaa loo qaataa irbad ahaan muruqa (intramuscular). Waxaa lagu bixiyaa laba qaybood oo kala duwan oo leh muddo laba ilaa lix bilood inta udhaxeysa Qiyaasta labaad waa lagama maarmaan si loo hubiyo waxtarka muddada-dheer.

Zostavax, oo la ansixiyay 2006, waa tallaal herpes zoster ah oo daciif ah. Si kale haddii loo dhigo, Zostavax waxa ku jira nooc daciif ah oo ah fayraska dhabta ah si loo soo saaro jawaab difaac. Sababtan awgeed, laguuguma talin kuwa tallaalka ka hortagga ah. Ama haddii kale, tallaalka laftiisu wuxuu sababi karaa caabuq.

Zostavax waxaa loo qaataa hal cirbad oo maqaarka hoostiisa ah (subcutaneous). Waxay ku timaaddaa a nooca la qaboojiyey iyo a nooca qaboojiyaha-deggan . Nooca la qaboojiyey waa in la dhigaa inta la qaboojinayo inta lagu jiro safarka iyo keydinta si loo hubiyo waxtarkeeda halka qaboojiyaha xasilloon ee Zostavax lagu hayn karo qaboojiyaha illaa inta loo baahan yahay in la isticmaalo.

Farqiga ugu weyn ee u dhexeeya Shingrix iyo Zostavax
	Shingrix	Zostavax
Fasalka daroogada	Tallaalka	Tallaalka
Summad / astaan guud	Magaca sumadda oo keliya	Magaca sumadda oo keliya
Waa maxay magaca guud?	Recombinant Tallaalka Zoster, Adjuvanted	Talaalka Zoster Live
Waa noocee (yada) daroogadu soo gasho?	Ka-hakinta duritaanka xididka	Ka-hakinta cirbadeynta subagga hoosteeda
Waa maxay qiyaasta caadiga ah?	Sii 1 qaadasho (0.5 ml) ka dibna qiyaas kale (0.5 ml) inta u dhexeysa 2 iyo 6 bilood kadib	Maamul hal qiyaas (0.65 ml) hal mar
Muddo intee le'eg ayaa daaweynta caadiga ah?	Talaalku wuxuu kudhamaaday 2 ilaa 6 bilood kadib 2 qaadasho	Tallaalku waa dhammaystirmaa 1 qaadasho ka dib
Ayaa si caadi ah u isticmaala daawada?	Dadka waaweyn ee jira 50 sano iyo wixii ka weyn	Dadka waaweyn ee jira 50 sano iyo wixii ka weyn

Xaaladaha ay daweeyeen Shingrix iyo Zostavax

Shingrix iyo Zostavax waa FDA loo ogolaaday ka hortagga shingles (herpes zoster). Labada tallaalba waxaa loo muujiyey inay ka hortagaan shingles-ka dadka waaweyn ee jira 50 sano iyo wixii ka weyn. Shingrix iyo Zostavax looma isticmaalo in looga hortago infekshinka asaasiga ah ee busbuska, oo sidoo kale loo yaqaan busbus.

Cudurka neuralgia ee 'Postherpetic neuralgia' waa nooc caadi ah oo xanuun dareemayaal ah oo ku yimaada shingles. Sababtoo ah Shingrix iyo Zostavax ayaa ka hortagi kara shingles, waxay sidoo kale ka hortagi karaan neuralgia gadaal dambe (PHN) iyo dhibaatooyinka kale ee xanuunka leh ee ka yimaada shingles. Hase yeeshe, tallaalladaan looma calaamadin inay daaweeyaan PHN.

Xaaladda	Shingrix	Zostavax
Ka hortagga herpes zoster (shingles)	Haa	Haa

Shingrix ama Zostavax waxtar badan ma leeyihiin?

Shingrix iyo Zostavax labaduba waa la xaqiijiyay inay ka hortagaan shingles. Si kastaba ha noqotee, Shingrix waa tallaal cusub oo loo arko inuu ka waxtar badan yahay Zostavax. Shingrix xitaa waa lagula taliyaa kuwa horey u qaatay talaalka Zostavax waagii hore.

Tijaabooyin caafimaad ayaa muujiyay in Shingrix uu yahay 97% wax ku ool ah ka hortagga shingles-ka ee dadka waaweyn ee jira 50 ilaa 69 sano jir. Shingrix sidoo kale waxay waxtar u leedahay ka hortagga shingles ee dadka waaweyn-dadka waaweyn ee ka weyn da'da 70, Shingrix waa 91% wax ku ool ah .

Zostavax wuxuu leeyahay a 70% waxtarka heerka ka hortagga shingles-ka ee dadka qaangaarka ah ee da'doodu tahay 50 illaa 69 sano jir, sida laga soo xigtay Tijaabada Zoster Waxqabadka iyo Badbaadada (ZEST). Natiijooyinka ka Daraasada Kahortaga Shingles muujiyey in Zostavax uu 51% waxtar ka leeyahay shingles. Marka loo barbardhigo Shingrix, waxtarka Zostavax wuxuu ku yaraanayaa kooxaha da'da weyn. Iyadoo lagu saleynayo natiijooyinka SPS, Zostavax wuxuu 64% waxtar u leeyahay dadka waaweyn ee jira 60 illaa 69 sano jir; 41% wax ku ool ah dadka waaweyn ee jira 70 illaa 79 sano jir; iyo 18% waxtar u leh dadka waaweyn ee jira 80 sano iyo wixii ka weyn.

Bixiyahaaga daryeel caafimaad ayaa u badan inuu kugula taliyo Shingrix in ka badan Zostavax. Shingrix waxaa si gaar ah lagula taliyaa bukaanada difaaca jirka iska difaaca maadaama ay tahay talaal aan nooleyn. Weydii dhakhtarkaaga ama farmashiistaha tallaalka shingles ee adiga kugu habboon.

Daboolida iyo qiimaha isbarbar dhiga Shingrix iyo Zostavax

Dadka waaweyn ee jira 50 sano iyo wixii ka weyn, kaliya qorshooyinka oo leh caymiska Medicare Qaybta D dabooli doonaa tallaalka Shingrix. Si kastaba ha noqotee, weli waxaa jiri kara lacag-bixin xitaa iyadoo ay jirto caymiska Medicare Qaybta D. Celcelis ahaan qiimaha lacagta caddaanka ah ee hal mar oo ah 'Shingrix dose' waa $ 167, inkasta oo laga yaabo inaad awoodo inaad isticmaasho kaarka qiime dhimista ee dhakhtar si aad u yareyso qiimahan. Ka hubi farmasiga deegaankaaga si aad u ogaato haddii aad isticmaali karto kaarka Shingrix SingleCare.

Sida Shingrix, Zostavax ugu horreyn waxaa daboola qorshayaasha Medicare Qaybta D ama qorshayaasha Faa'iidada Medicare oo leh caymiska Medicare Qaybta D. Bixinta Zostavax ee caymiska way kala duwanaan kartaa. Qiyaasta celceliska lacagta caddaanka ah ee $ 278, Zostavax way qaali noqon kartaa caymis ama aan lahayn. Isticmaalka kaarka qiimo dhimista rijeetada ee loo yaqaan 'Zostavax' ayaa laga yaabaa inuu kaa yareeyo kharashkan.

	Shingrix	Zostavax
Caadi ahaan caymiska ayaa daboolaya?	Haa	Haa
Caadi ahaan waxaa daboola Medicare Qaybta D?	Haa	Haa
Qiyaasta caadiga ah	1 duritaan (0.5 ml) ka dibna irbad kale (0.5 ml) 2 ilaa 6 bilood kadib	1 cirbad hal-qaadasho ah (0.65 ml)
Bixinta lacagta caadiga ah ee 'Medicare'	$ 0– $ 164	$ 0– $ 237
Qiimaha SingleCare	$ 155 +	N / A

Dhibaatooyinka guud ee Shingrix iyo Zostavax

Saameynaha ugu caansan ee Shingrix iyo Zostavax waxay ku lug leeyihiin falcelin goobta duritaanka. Cirbadda Shingrix ama Zostavax ka dib, waxaad la kulmi kartaa xanuun, guduudasho, ama barar ku wareegsan goobta duritaanka. Waxa kale oo aad dareemi kartaa xanuun ama cuncun agagaarka aagga duritaanka.

Marka loo barbardhigo Zostavax, Shingrix waxaa lagu soo warramey inay keento falcelinno nidaamsan oo badan sida madax xanuun, qandho, murqo xanuun (myalgia), iyo daal. In kasta oo waxyeelooyinkan laga yaabo inay dhib badan yihiin, haddana caadi ahaan waa kuwo khafiif ah oo iskood u baaba'a.

	Shingrix	Zostavax
Waxyeellada	Ma khuseysaa?	Joogtaynta	Ma khuseysaa?	Joogtaynta
Guduudasho goobta duritaanka	Haa	39%	Haa	36%
Xanuun ka jira goobta la muday	Haa	86%	Haa	3. 4%
Barar barta duritaanka	Haa	29%	Haa	26%
Cuncun meesha laga muday	Haa	laba%	Haa	7%
Madax xanuun	Haa	Afar. Shan%	Haa	1%
Qandho	Haa	26%	Haa	laba%
Murqo xanuun	Haa	53%	Maaha	*
Daal	Haa	51%	Maaha	*

* lama soo sheegin
Joogtayntu kuma salaysna xogta laga soo qaaday tijaabo madax-ilaa-madax ah. Tani ma noqon karto liistada dhameystiran ee waxyeelooyinka xun ee dhici kara. Fadlan tixraac dhakhtarkaaga ama daryeel caafimaad si aad wax badan uga ogaato.
Xigasho: DailyMed (Shingrix) , DailyMed (Zostavax)

Isdhexgalka daroogada ee Shingrix iyo Zostavax

Daawooyinka difaaca jirka sida cyclosporine iyo tacrolimus waxay yareyn karaan waxtarka tallaalada. Daawooyinka isteeroydhiska, sida prednisone, iyo kemotherabi sidoo kale waxay yeelan karaan saameyn isdaba-joog ah oo wax ka beddeli kara sida tallaaladu u shaqeeyaan.

Kuwa ku jira daaweynta difaaca jirka waa inay ka fogaadaan gebi ahaanba Zostavax; Zostavax waxaa kujira fayraska nool, oo sababi kara infekshan.

Daawooyinka fayraska ka hortaga sida acyclovir iyo famciclovir waxay faragalin ku yeelan karaan saameynta tallaalka Zostavax. Guddiga La-talinta ee Ku-Dhaqanka Tallaalada (ACIP) waxay ku talinayaan in dadka ku jira daawooyinka ka hortagga fayraska ay joojiyaan qaadashada daawooyinka fayraska looga hortago 24 saac kahor qaadashada tallaalka Zostavax. Daaweynta dawooyinka ka hortaga fayraska waa inaan dib loo bilaabin ugu yaraan 14 maalmood tallaalka Zostavax kadib.

Daroogada	Fasalka Daroogada	Shingrix	Zostavax
Cyclosporine Tacrolimus Prednisone Dawaynta kimikalka	Daaweynta Immunosuppressive	Haa	Haa
Acyclovir Valacyclovir Famciclovir	Wakiilada fayraska	Maaha	Haa

Kala tasho xirfadle daryeel caafimaad isdhexgalka kale ee dawooyinka ee suurtogalka ah

Digniinta Shingrix iyo Zostavax

Shingrix iyo Zostavax waxay sababi karaan xasaasiyad, ama xasaasiyad, xasaasiyadda kuwa xasaasiyadda ku leh maaddooyinka tallaalka. Zostavax wuxuu sababi karaa falcelin xasaasiyadeed oo daran kuwa xasaasiyadda ku leh gelatin ama neomycin. Dareen-celinta xasaasiyadeed ee daran waxay u horseedi kartaa firiiric daran iyo neefsashada oo dhib ah (anaphylaxis).

Zostavax waa in laga fogaadaa kuwa qaata walxaha difaaca jirka difaaca iyo kuwa ay saameeyaan xaaladaha caafimaad ee daciifa nidaamka difaaca jirka.

Weydii dhakhtarkaaga ama farmashiistaha waxyaabaha ku saabsan taxaddarrada kale ka hor intaadan qaadan tallaalka shingles.

Su'aalaha badanaa la isweydiiyo ee ku saabsan Shingrix vs. Zostavax

Waa maxay Shingrix?

Shingrix waa a tallaalka recombinant loo isticmaali jiray in looga hortago herpes zoster, ama shingles, ee dadka waaweyn ee jira 50 sano ama ka weyn. Waxaa la ansixiyay sanadkii 2017, Shingrix waa tallaal aan firfircooneyn oo aan ku jirin fayraska noolaha 'varicella-zoster virus'. Waxaa lagu qaataa laba qiyaasood oo leh labo ilaa lix bilood inta udhaxeysa qiyaasta koowaad iyo tan labaad. Shingrix waxaa soo saaray shirkadda GlaxoSmithKline.

Waa maxay Zostavax?

Zostavax waa tallaal sifeyn kufilan oo sawir qaade ah oo FDA la ansixiyay 2006. Maaddaama uu yahay tallaal nool oo la dhimay, Zostavax waxaa ku jira nooc nool oo daciif ah oo ah fayraska 'varicella-zoster virus'. Zostavax waxaa lagu siiyaa hal qaadasho dadka waaweyn ee jira 50 sano ama ka weyn. Waxaa soo saaray shirkadda Merck.

Shingrix iyo Zostavax ma isku mid baa?

Shingrix iyo Zostavax labaduba waxay yareyn karaan halista shingles. Si kastaba ha noqotee, waxay ku kala duwan yihiin waxtarka, maamulka, iyo dhibaatooyinka soo raaca. Shingrix waa tallaal dib-u-cusboonaysiin ah oo loo yaqaan 'zoster' iyo 'Zostavax' waa tallaal nool. Micnaha, Shingrix wuxuu kakooban yahay qaab aan nooleyn oo ah fayraska 'varicella-zoster virus' iyo 'Zostavax' waxaa kujira qaab noole, daciif ah oo virus ah. Farqiga kale ayaa ah in Shingrix lagu mudo muruqa halka Zostavax lagu duray maqaarka hoostiisa. Marka loo barbardhigo Zostavax, Shingrix waa tallaal shingles cusub.

Shingrix ama Zostavax ma ka fiican yihiin?

Shingrix ayaa ka waxtar badan Zostavax. Shingrix wuxuu 97% waxtar u leeyahay kahortaga shingles-ka dadka qaangaarka ah ee da'doodu udhaxeyso 50 ilaa 69 sano halka Zostavax kaliya 70% ay waxtar u leedahay kahortaga shingles isla da'da kooxeed. Shingrix waxay si isdaba joog ah uga hortagtaa nabarrada ku dhaca dadka waayeelka ah halka waxtarka Zostavax uu hoos u dhacayo da'da sii kordheysa. Si kastaba ha noqotee, Shingrix waxay leedahay waxyeellooyin dhinaca nidaamka ah oo ka badan Zostavax.

Ma isticmaali karaa Shingrix ama Zostavax inta aan uurka leeyahay?

Xarumaha Xakamaynta iyo Kahortagga Cudurrada (CDC) kuma talinayaan Shingrix ama Zostavax haweenka uurka leh. Ma jiraan daraasado ku filan oo lagu ogaanayo amniga Shingrix ama Zostavax ee haweenka uurka leh . La tasho dhakhtarkaaga ama daryeel caafimaad bixiyahaaga kahor intaadan qaadan tallaalka shingles.

Ma ku isticmaali karaa Shingrix ama Zostavax aalkolo?

Cabitaanka khamrigu ma beddelayo waxtarka Shingrix ama Zostavax. Guud ahaan waa ammaan in si dhexdhexaad ah wax loo cabbo ka dib marka lagu tallaalo tallaalka shingles.

Mudo intee le'eg ayuu soconayaa tallaalka Shingrix?

Tijaabooyin caafimaad ayaa muujiyay in Shingrix wuxuu weli shaqeynayaa ugu yaraan afar sano qaadashada labaad kadib. Waxaa la soo jeediyay in Shingrix uu xitaa sii dheeraado intaas. Weli, daraasado dheeraad ah ayaa lagu sameeyaa waxtarka Shingrix muddada fog.

Muddo intee le'eg ayuu waxtar leeyahay Zostavax?

Kahortaga shingles waa mid soconaya shan sano kadib tallaalka Zostavax . Shan sano kadib, waxtarka Zostavax wuu yaraan karaa waqtiga. CDC waxay kugula talineysaa inaad hesho tallaalka cusub ee shingles, Shingrix, xitaa haddii aad horey u heshay tallaalka Zostavax waqti hore.

Maxaa dhacaya haddii aadan helin tallaalka labaad ee Shingrix?

Talaalka labaad ee Shingrix wuxuu muhiim u yahay in la hubiyo in tallaal buuxa laga hortago. Si kastaba ha noqotee, uma baahnid inaad ka walwasho haddii in ka badan lix bilood ay dhaaftay ka hor intaadan helin tallaalka xoojinta. Kaliya iska hubi inaad heshay tallaalka labaad sida ugu dhow muddada laba ilaa lix bilood sida ugu macquulsan.