Vascepa iyo Lovaza: Kala duwanaanshaha, isku ekaanshaha, iyo yaa adiga kuu fiican
Daroogada Vs. SaaxiibDulmarka daroogada & kala duwanaanshaha ugu weyn | Xaaladaha la daweeyay | Wax ku oolnimada | Caymiska caymiska iyo isbarbardhiga qiimaha | Dhibaatooyinka ay keento | Isdhexgalka daroogada | Digniinta | Su'aalaha
Hadaad leedahay triglycerides sare , Waxaa laga yaabaa in dhakhtarkaagu kuu sheegay inaad tijaabiso cuntada iyo jimicsiga, iyo malaha sida Lipitor oo kale. Waxa kale oo laga yaabaa inaad maqashay astaamaha dufanka omega-3, ama kaabisyada saliidda kalluunka.
Vascepa iyo Lovaza waa laba daawo oo caan ah oo lagu magacaabo omega-3 oo ah dufanka aashitada ee daweeya heerarka triglyceride ee sarreeya. Labada daawoba waxaa ansaxiyay Maamulka Cuntada iyo Dawooyinka ee Maraykanka (FDA). Amarin Pharma, Inc. ayaa sameysa Vascepa, halka GlaxoSmithKline ay sameyso magaca nooca loo yaqaan Lovaza. Daawooyinkani waxay u shaqeeyaan dhowr siyaabood oo lagu yareeyo triglycerides. In kasta oo labada daawoba ay yihiin omega-3 dheeri ah, si sax ah iskuma mid aha. Sii wad aqrinta si aad waxbadan uga barato Vascepa iyo Lovaza.
Maxay ku kala duwan yihiin Vascepa iyo Lovaza?
Vascepa iyo Lovaza waxaa loo qoondeeyay inay yihiin dawooyinka loo qoro omega-3 dufanka xaydha yareysa. Vascepa waxaa hadda lagu heli karaa magaca sumadda, halka Lovaza lagu heli karo nooc iyo astaan guud (omega-3-acid ethyl esters). Labada daroogoba waa loo oggol yahay isticmaalka dadka waaweyn mana lagu baran carruurta.
Vascepa waxaa ku jira maaddada icosapent ethyl, ama ethyl ester ee eicosapentaenoic acid (EPA). Vascepa waxay hoos u dhigtaa triglycerides waxayna kaa caawin kartaa kahortaga dhibaatooyinka wadnaha iyo xididada bukaanka khatarta sare leh qaarkood.
Lovaza waxaa ku jira omega-3-acid ethyl esters, inta badan eicosapentaenoic acid (EPA) iyo docosahexaenoic acid (DHA). Lovaza waxay hoos u dhigtaa triglycerides laakiin waxay kordhin kartaa kolestaroolka LDL. Sidaa darteed, saameynta ay ku leedahay cudurka wadnaha iyo xididdada lama yaqaan.
| Farqiga ugu weyn ee u dhexeeya Vascepa iyo Lovaza | ||
|---|---|---|
| Vascepa | Lovaza | |
| Fasalka daroogada | Omega-3 wakiilka subag-yareynta dufanka leh ee Omega-3 | Omega-3 wakiilka subag-yareynta dufanka leh ee Omega-3 |
| Summad / astaan guud | Summad | Summad iyo astaan guud |
| Waa maxay magaca guud? | Icosapent ethyl ama ethyl ester ee eicosapentaenoic acid (EPA) | Omega-3-acid ethyl esters: eicosapentaenoic acid (EPA) iyo docosahexaenoic acid (DHA) |
| Waa noocee (yada) daroogadu soo gasho? | Kaabsoosha | Kaabsoosha |
| Waa maxay qiyaasta caadiga ah? | 4 garaam maalintiiba qiyaasood oo kala qaybsan (cunto lagu qaato): 2, 1 garaam oo kaabsol ah laba jeer maalintii ama 4, 0.5 garaam oo kaabsol ah laba jeer maalintii Kaabsal liq oo dhan. Ha furin, calalin, ha milmin, ama ha burburin. | 4 garaam maalintii: 4, 1 garaam oo kaabsal ah hal mar maalintii ama 2, 1 garaam kaabsal laba jeer maalintii Kaabsal liq oo dhan. Ha furin, calalin, ha milmin, ama ha burburin. |
| Muddo intee le'eg ayaa daaweynta caadiga ah? | Kaladuwan | Kaladuwan |
| Ayaa si caadi ah u isticmaala daawada? | Dadka waaweyn | Dadka waaweyn |
Ma dooneysaa qiimaha ugu fiican Vascepa?
Isu qor digniinta qiimaha Vascepa oo ogow goorta sicirka isbeddelo!
Hel digniinta qiimaha
Xaaladaha ay daweeyeen Vascepa iyo Lovaza
Labadaba Vascepa iyo Lovaza waxaa loo tilmaamay in loo isticmaalo kaabista cuntada si loo yareeyo triglycerides ee dadka waaweyn ee leh triglycerides aad u sarreeya (≥ 500 mg / dL).
Vascepa sidoo kale waa la isticmaali karaa iyada oo ay weheliso qiyaasta ugu badan ee daaweynta statin si loo yareeyo halista dhacdooyinka wadnaha iyo wadnaha (istaroogga wadnaha, istaroogga, dib u soo celinta wadnaha, xasiloonida angina) ee dadka qaangaarka ah ee leh triglycerides ≥ 150 mg / dL kuwaas oo sidoo kale qaba cudurrada wadnaha iyo xididada dhiigga, ama kuwa qaba sonkorowga mellitus iyo laba ama in ka badan oo kale qatarta wadnaha cudur).
Saamaynta Vascepa iyo Lovaza ee halista ganaca ee bukaanka qaba triglycerides aad u sarreeya lama oga.
Sidoo kale, saameynta Lovaza ee cudurka wadnaha iyo geerida lama yaqaan.
| Xaaladda | Vascepa | Lovaza |
| Waxaa loo adeegsaday qiyaasta sare ee statin si loo yareeyo dhibaatooyinka wadnaha iyo xididada ee dadka waaweyn ee leh triglycerides ≥ 150 mg / dL | Haa | Maaha |
| Waxaa loo adeegsaday cunto si loo yareeyo heerarka triglyceride ee dadka waaweyn ee qaba hypertriglyceridemia daran (≥500 mg / dL) | Haa | Haa |
Vascepa ama Lovaza waxtar badan ma leeyihiin?
Gudaha barasho isbarbardhigga asiidhka dufanka ee omega-3, qorayaashu waxay ku soo gabagabeeyeen in daawooyinkani ay si weyn hoos ugu dhigi karaan triglycerides ilaa heer la barbardhigi karo guud ahaanna si wanaagsan loo dulqaadan karo Daawooyinka sida Lovaza, oo ka kooban DHA, waxay kordhin karaan LDL kolestaroolka, oo dhib ku noqon kara bukaannada halista sare ugu jira cudurrada wadnaha iyo xididdada. Vascepa waxaa ku jira oo keliya EPA mana saameynayso heerarka LDL.
Bixiyahaaga daryeelka caafimaad ayaa go'aamin kara daawada kuugu waxtar badan. La tasho daryeel caafimaad bixiyahaaga wixii talo caafimaad ah. Isaga ama iyada ayaa go'aan ka gaari kara haddii Vascepa ama Lovaza ay adiga kugu habboon yihiin markaad tixgelinayso xaaladahaaga caafimaad iyo taariikhdaada iyo daawooyinka aad qaadato ee la falgalaya Vascepa ama Lovaza.
Marabtaa qiimaha ugu fiican Lovaza?
Isu qor digniinta qiimaha Lovaza oo ogow goorta sicirka isbeddelo!
Hel digniinta qiimaha
Daboolida iyo qiimaha isbarbar dhiga Vascepa iyo Lovaza
Qorshayaasha caymiska iyo qorshooyinka rijeetada ee Medicare ayaa sida caadiga ah daboolaya Vascepa iyo Lovaza. Haddii aad qaadato Lovaza, xulashada foomka guud wuxuu badbaadin karaa lacag aad u tiro badan, iyadoo kuxiran qorshahaaga.
Qiimaha jeebka ka baxa ee bixinta billaha ah ee Vascepa waa qiyaastii $ 390, laakiin waxaad isticmaali kartaa kaarka 'SingleCare' oo bilaash ah si aad qiimaha ugu dhigto qiyaastii $ 332.
Bixin hal bil ah oo loo yaqaan 'Lovaza' guud ahaan waa $ 100 haddii aad jeeb ka bixiso. Kuuboon SingleCare oo bilaash ah ayaa hoos u dhigi kara qiimaha wax ka yar $ 30.
La xiriir qorshahaaga caymiska si aad u hesho macluumaadka ugu dambeeyay ee caymiska.
| Vascepa | Lovaza | |
| Caadi ahaan caymiska ayaa daboolaya? | Haa | Haa |
| Caadi ahaan waxaa daboola Medicare Qaybta D? | Haa | Haa |
| Qiyaasta caadiga ah | 120, 1 kaabsal gram | 120, 1 kaabsal gram |
| Bixinta lacagta caadiga ah ee 'Medicare' | $ 1- $ 3 | $ 1- $ 30 |
| Qiimaha SingleCare | $ 332 + | $ 30 + |
Dhibaatooyinka guud ee Vascepa iyo Lovaza
Waxyeelada ugu badan ee Vascepa waa muruq xanuun, barar durugsan (gacmaha ama lugaha oo barar), calool istaag, gout, iyo fibrillation-ka jirka. Dhibaatooyinka kale ee soo raaca waxaa ka mid noqon kara shuban ama calool xanuun.
Saameynaha ugu caansan ee Lovaza waa belching, dheefshiidka, iyo dhadhanka la beddelay. Dhibaatooyinka kale ee soo raaca ayaa dhici kara, sida calool istaag, matag, iyo finan.
Tani ma aha liistada dhammaystiran ee waxyeellooyinka soo raaca. Waxyeellooyin kale ayaa dhici kara. La tasho xirfadlahaaga daryeelka caafimaadka liistada buuxda ee waxyeelooyinka xun.
| Vascepa | Lovaza | |||
| Waxyeellada | Ma khuseysaa? | Joogtaynta | Ma khuseysaa? | Joogtaynta |
| Murqo xanuun | Haa | ≥3% | Maaha | - |
| Barar durugsan | Haa | ≥3% | Maaha | - |
| Calool fadhiga | Haa | ≥3% | Haa | % lama sheegin |
| Turqo | Haa | ≥3% | Maaha | - |
| Cudurka 'Atrial fibrillation' | Haa | ≥3% | Haa | % lama sheegin |
| Belching | Maaha | - | Haa | 4% |
| Dheef-shiidka | Maaha | - | Haa | 3% |
| Dhadhankii la beddelay | Maaha | - | Haa | 4% |
Xigasho: DailyMed ( Vascepa ), DailyMed ( Lovaza )
Isdhexgalka daroogada ee Vascepa iyo Lovaza
Sida lagu sharxay macluumaadka qoritaanka ee Vascepa iyo Lovaza, daraasado kiliinik ah oo lagu sameeyay omega-3 asiidh dufan leh sida Vascepa iyo Lovaza waxay muujiyeen waqtiga dhiigbaxa dheeri ee bukaanka, laakiin waqtigu kama badnayn xadka caadiga ah, dhacdooyinkuna caafimaad ahaan muhiim ma ahan. Haddii Vascepa ama Lovaza lala qaato daawada xinjirowga lidka ku ah (dhiig khafiifiyaha) ama daawada antiplatelet, la soco bukaanka dhiigbaxa. U sheeg daryeel caafimaad bixiyahaaga dhammaan daawooyinka aad qaadato, oo ay ku jiraan dawooyinka laguu qoro, daawooyinka aad iska iibsato (OTC), iyo nafaqada dheeriga ah.
| Daroogada | Fasalka daroogada | Vascepa | Lovaza |
| Arixtra (fondaparinux) Coumadin (warfarin) Eliquis Heparin Lovenox (enoxaparin) Pradaxa Savaysa Xarelto | Anticoagulants | Haa | Haa |
| Aspirin Brilinta Dipyridamole Adkaysi (prasugrel) Plavix (clopidogrel) | Wakiilada Antiplatelet | Haa | Haa |
Digniinta Vascepa iyo Lovaza
- Labada indhoole, tijaabooyinka kiliinikada kontoroolka ah, Vascepa iyo Lovaza waxay la xiriireen halista sii kordheysa ee fibrillation-ka wadnaha ama qulqulka wadnaha, taas oo u baahan isbitaal dhigid. Dhacdadu way ka badan tahay bukaanka qaba taariikh fiiq-fiiqid ama qulqulatada wadnaha.
- Vascepa iyo Lovaza waxaa ku jira asiidh dufan leh oo ka yimaada saliida kalluunka. Ma cadda in bukaanada qaba xasaasiyadda kalluunka ama kalluunka qolofta leh ay qatar ugu jiraan xasaasiyadda Vascepa ama Lovaza. Ka feejignow suurogalnimada falcelin xasaasiyadeed, oo raadso daryeel caafimaad oo degdeg ah haddii fal-celin dhacdo.
- Tijaabooyinka caafimaad, Vascepa iyo Lovaza waxay la xiriireen halista sare ee dhiigbaxa. Khatartu waxay ku badan tahay bukaanada qaata dawooyinka xinjirowga lidka ku ah ama dawooyinka kahortagga. Ka eeg qaybta isdhexgalka daroogada wixii macluumaad dheeraad ah.
- Bukaannada qaba dhibaatooyinka beerka, la soco AST iyo ALT inta lagu jiro daweynta.
- Liq Vascepa ama kaabsoosha Lovaza oo dhan. Ha calalin ama ha burburin.
- Lovaza waxay kordhin kartaa heerarka LDL kolestaroolka (ama LDL-C) - kormeer heerarka LDL inta lagu jiro daaweynta Lovaza.
Su'aalaha badanaa la isweydiiyo ee ku saabsan Vascepa vs. Lovaza
Waa maxay Vascepa?
Vascepa waa daawo qoro asiidh dufan ah oo omega-3 ah oo ka kooban maado la yiraahdo EPA (ethyl ester of eicosapentaenoic acid). Vascepa waxay caawisaa yareynta heerarka triglyceride.
Waa maxay Lovaza?
Lovaza waa daawo qoris asiidh dufan ah oo omega-3 ah oo loo isticmaalo in lagu yareeyo triglycerides. Lovaza waxaa ku jira eicosapentaenoic acid (EPA) iyo docosahexaenoic acid (DHA).
Vascepa iyo Lovaza ma isku mid baa?
Labada daawoba waa isku mid. Vascepa iyo Lovaza labaduba waa omega-3 dufanka asiidhka dufanka leh oo lagu heli karo warqad dhakhtar si loo yareeyo triglycerides. Labada daawoba waxay kakoobanyihiin EPA; Lovaza sidoo kale waxay ka kooban tahay DHA. Kala duwanaanshaha kale ayaa kor lagu soo sheegay.
Vascepa ama Lovaza ma ka fiican yihiin?
Vascepa iyo Lovaza ayaa la barbardhigi karaa markay hoos u dhigayaan triglycerides. Waxay sidoo kale guud ahaan si fiican loo dulqaatay. Hal farqi ayaa ah in Vascepa uusan saameyn ku yeelan heerarka LDL, laakiin Lovaza waxay kordhin kartaa heerarka LDL ee bukaannada qaar. Tani waxay saameyn ku yeelan kartaa daawada uu takhtarkaagu doorto, iyadoo ku xiran sababaha halista u ah cudurka wadnaha.
Ma isticmaali karaa Vascepa ama Lovaza inta aan uurka leeyahay?
Ma jiro macluumaad ku filan oo la heli karo si loo ogaado haddii Vascepa ama Lovaza ay nabdoon yihiin muddada uurka. La tasho daryeel caafimaad bixiyahaaga haddii aad uur leedahay ama aad qorsheyneyso inaad uur yeelato.
Ma ku isticmaali karaa Vascepa ama Lovaza aalkolo?
Macluumaadka lagu qoro Vascepa iyo Lovaza ma tilmaamayo tilmaamaha la xiriira isticmaalka khamriga. La tasho daryeel caafimaad bixiyahaaga ku saabsan isticmaalka aalkolada iyo xaaladahaaga caafimaad.
Vascepa ma la mid tahay saliidda kalluunka?
Vascepa waxaa ku jira kaliya hal maado, EPA. Saliidaha kalluunka, sida Lovaza, guud ahaan waxay ka kooban yihiin EPA iyo DHA.
EPA waxay yareysaa triglycerides, laakiin DHA waxay kordhin kartaa kolestaroolka LDL. Maaddaama Vascepa ay leedahay oo keliya EPA, waxay hoos u dhigtaa triglycerides laakiin ma kordhinayso kolestaroolka LDL.
Immisa ayuu hoos u dhigaa Lovaza triglycerides?
Gudaha daraasadaha caafimaadka , Lovaza wuxuu yareeyay triglycerides celcelis ahaan qiyaastii 45%.
Vascepa ma yahay anti-bararka?
Qaabka ay Vascepa ugu shaqeyso yareynta triglycerides si buuxda looma fahmin laakiin waxay u badan tahay inay ku shaqeyso dhowr qaab. In 2018, Amarin Corporation, soo saaraha Vascepa, waa la sii daayay natiijooyinka daraasadda gabagabeynaya in Vascepa ay yareysey calaamadaha caabuqa ee bukaanjiifka qaarkood. Si kastaba ha noqotee, Vascepa looma kala qoro daroogada anti-bararka.
