Lomotil iyo Imodium: Kala duwanaanshaha, isku ekaanshaha, iyo yaa adiga kuu fiican
Waxbarashada CaafimaadkaDulmarka daroogada & kala duwanaanshaha ugu weyn | Xaaladaha la daweeyay | Wax ku oolnimada | Caymiska caymiska iyo isbarbardhiga qiimaha | Dhibaatooyinka ay keento | Isdhexgalka daroogada | Digniinta | Su'aalaha
Lomotil (diphenoxylate / atropine) iyo Imodium (loperamide) waa laba daawo oo shuban biyoodka loo isticmaalo oo lagu daweeyo shuban joogto ah . Daawooyinkani waxay u shaqeeyaan siyaabo isku mid ah si loo yareeyo tirada iyo inta jeer ee saxaroowga. Lomotil iyo Imodium waxaa loogu talagalay in loo qaado shuban muddo-gaaban ah, kaas oo badanaa lagu xalliyo dhawr maalmood gudahood ka dib marka la qaato daawada.
Xaalado badan, shubanku, in kasta oo uu yahay khibrad aan fiicnayn, haddana inta badan waa khafiif oo kaligiis ayuu iska tagaa. Daaweynta aasaasiga ah ee shubanka waa beddelidda dheecaannada iyo elektarolaytyada si looga hortago fuuqbaxa. Si kastaba ha noqotee, daawooyinka sida Lomotil iyo Imodium waxay faa'iido u yeelan karaan shuban ba'an iyo sidoo kale shuban joogto ah oo la xiriira cilladda mindhicirka xanaaqa (IBS).
In kasta oo ay iskaga mid yihiin adeegsiga, Lomotil iyo Imodium waxay leeyihiin kala duwanaansho ay tahay in laga fekero. Tusaale ahaan, daawooyinkani waxay ka kooban yihiin maaddooyin kala duwan waxayna leeyihiin xadad gaar ah. Waxaan ku baari doonnaa kala duwanaanshahooda iyo waxyaabaha ay iska shabahaan halkan.
Maxay ku kala duwan yihiin Lomotil iyo Imodium?
Lomotil
Lomotil waa daawo magac ku caan ah oo lagu heli karo oo keliya warqad dhakhtar qoro. Waxay ka kooban tahay isku darka 'diphenoxylate' (opioid) iyo atropine (daawada xinjirowga lidka ku ah).
Diphenoxylate waa maaddada asaasiga ah ee ku xirta qabtayaasha opioid ee mindhicirka si loo yareeyo dhaqdhaqaaqa xiidmaha. Atropine waxaa lagu daraa si looga hortago xadgudubka daroogada maaddaama diphenoxylate uu yahay walax la kontoroolo kaligiis.
Imodium
Imodium, sidoo kale loo qaabeeyey Imodium A-D, waa magaca sumadda loogu talagalay loperamide. Si ka duwan Lomotil, Imodium waxaa laga iibsan karaa miiska (OTC). Sidaa darteed, si ballaadhan ayaa loo heli karaa.
Loperamide waa opioid synthetic ah oo kuxiran qabtayaasha opioid ee xiidmaha mindhicirka si loo yareeyo dhaqdhaqaaqa mindhicirka. Waxay sidoo kale xannibtaa kiimiko loo yaqaan acetylcholine waxayna keentaa hoos u dhaca dareeraha iyo luminta elektroolka. Sababtoo ah Imodium waxay leedahay nuugista ugu yar ee habka dhexe ee neerfaha (CNS), waxay soo saartaa waxyeellooyin yar oo CNS ah oo caan ku ah opioids kale, oo ay ku jiraan diphenoxylate.
| Farqiga ugu weyn ee u dhexeeya Lomotil iyo Imodium | ||
|---|---|---|
| Lomotil | Imodium | |
| Fasalka daroogada | Shuban-biyoodka | Shuban-biyoodka |
| Summad / astaan guud | Nooc nooc iyo nooc guud ah ayaa la heli karaa | Nooc nooc iyo nooc guud ah ayaa la heli karaa |
| Waa maxay magaca guud? | Diphenoxylate / Atropine | Loperamide |
| Waa noocee (yada) daroogadu soo gasho? | Kiniin afka ah Xalka dareeraha | Kiniin afka ah Kaabsal afka ah Ka joojinta dareeraha |
| Waa maxay qiyaasta caadiga ah? | Shuban-biyood ba'an: 2 kiniin (2.5 mg diphenoxylate / 0.025 mg atropine) afar jeer maalintii ilaa inta laga gaarayo xakamaynta shubanka. Shuban joogto ah Ku yaree qiyaasta bilowga ah qiyaasta dayactirka (badanaa 2 kiniin maalin kasta) sida uu takhtarku ku faro. Jooji haddii astaamuhu ku fiicnaan waayaan 10 maalmood gudahood. | Shuban-biyood ba'an: 4 mg bilow, ka dibna 2 mg saxarada dabacsan kadib. Qiyaasta ugu badan ee maalinlaha ah: 16 mg Shuban joogto ah Isticmaal qiyaasta dayactirka ee 4 ilaa 8 mg maalintii. Jooji haddii astaamuhu ku fiicnaan waayaan 10 maalmood gudahood. |
| Muddo intee le'eg ayaa daaweynta caadiga ah? | Shuban muddo-gaaban ah oo lagu xalliyo 10 maalmood gudahood. Isticmaalka muddada-dheer waxaa laga yaabaa in looga baahdo shubanka daba-dheeraada. | Shuban muddo-gaaban ah oo lagu xalliyo 10 maalmood gudahood. Isticmaalka muddada-dheer waxaa laga yaabaa in looga baahdo shubanka daba-dheeraada. |
| Ayaa si caadi ah u isticmaala daawada? | Dadka waaweyn iyo carruurta jirta 13 sano iyo wixii ka weyn. | Dadka waaweyn iyo carruurta jirta 2 sano iyo wixii ka weyn. Carruurta ka yar 6 sano waa inay la tashadaan dhakhtar ka hor inta aysan qaadan dareeraha Imodium. |
Ma dooneysaa qiimaha ugu fiican ee Lomotil?
Saxiix ogeysiisyada qiimaha Lomotil oo ogow goorta sicirka isbeddelo!
Hel digniinta qiimaha
Xaaladaha ay daweeyeen Lomotil iyo Imodium
Lomotil waa FDA-loo ansixiyay inay tahay daaweyn isdaba joog ah oo loogu talagalay shubanka. Tani waxay ka dhigan tahay in Lomotil lagula taliyo daaweyn dheeraad ah oo ay weheliso hababka daaweynta aasaasiga ah sida ka hortagga fuuqbaxa.
Sida Lomotil, Imodium waa FDA-ogolaatay in lagu daaweeyo dhowr nooc oo shuban ah. Imodium waa loo isticmaali karaa in lagu daaweeyo Shuban-socotada iyo sidoo kale shuban ka dhasha dawooyinka sida kiimoteraabiga. Lomotil iyo Imodium waxay kaloo daaweyn karaan shuban-biyoodka joogtada ah ee ay keento cilladda mindhicirka xanaaqa (IBS).
Shubanka waxaa caadi ahaan lagu qeexaa inuu yeesho saxaro dabacsan saddex jeer ama ka badan hal maalin. Cudurka shuban biyoodka badanaa waa mid fudud oo badiyaa wuxuu socdaa wax aan ka badnayn hal ama laba maalmood. Sunta cuntada waa sababaha ugu badan ee sababa shuban biyoodka.
Shuban joogto ah waa mid daran oo socon kara in ka badan afar toddobaad markiiba. Calaamadaha shubanku iskood ayey u bixi karaan ama wey sii socon karaan muddo aad u dheer, taas oo u baahan karta daaweyn daawo.
| Xaaladda | Lomotil | Imodium |
| Shuban-biyood ba'an | Haa | Haa |
| Shuban-socotada | Haa | Haa |
| Shuban joogto ah | Haa | Haa |
| Shuban-biyoodka la xiriira kemotherabi | Haa | Haa |
Lomotil ama Imodium ma ka waxtar badan yihiin?
Lomotil iyo Imodium ayaa ah kuwa ugu badan ee loo isticmaalo dawooyinka shubanka. Labadooduba waa kuwo waxtar leh oo si dhakhso leh u shaqeeya si ay u yareeyaan astaamaha cudurka shubanka. Daawada ugu fiican ee adiga kugu habboon waxay ku xirnaan doontaa xaaladdaada guud, taasoo ay tahay inuu qiimeeyo bixiyahaaga daryeelka caafimaad.
Taas markii la dhaho, Imodium waxay noqon kartaa daawada ugu waxtarka badan. In kasta oo aysan jirin tijaabooyin caafimaad oo si toos ah isu barbar dhiga Lomotil iyo Imodium, haddana daraasadaha qaarkood waxay soo jeedinayaan in Imodium uu yahay xulasho la doorbido oo lagu daaweeyo shubanka. Mid laba-indhoole ah, barashada iskutallaabta waxay ogaatay in loperamide uu ka sareeyo diphenoxylate ee daaweynta shubanka xitaa qiyaas 2.5-laab hoose ah.
Midkale barashada iskutallaabta marka la barbardhigo loperamide, diphenoxylate, iyo codeine oo lagu daaweeyo shubanka joogtada ah. Daaweynta ka hor, 95% kaqeybgalayaashu waxay la kulmeen xaalad deg deg ah oo ah astaamahooda ugu weyn ee shubanka. Daraasadu waxay ogaatay in loperamide iyo codeine ay ka waxtar badan yihiin diphenoxylate ee gargaarka. Diphenoxylate waxaa lagu ogaadey inuu leeyahay waxyeelada ugu badan halka loperamide la muujiyey inuu ugu yaryahay.
Daboolida iyo qiimaha isbarbar dhiga Lomotil iyo Imodium
Inta badan Medicare Qeybta D iyo qorshayaasha caymiska ma daboolaan magaca magaca Lomotil. Si kastaba ha noqotee, qorshooyin badan oo caymis ayaa daboolaya nooca guud ee daroogada. Qorshayaasha Medicare Qaybta D waa inay daboolaan diphenoxylate / atropine iyadoo kuxiran caymiskaaga. Celceliska qiimaha tafaariiqda ee guud ahaan Lomotil waa ilaa $ 38. Ka hubi farmasigaaga si aad u ogaato haddii aad isticmaali karto kaarka lacag-dhimista. Kuuboonada SingleCare Lomotil waxay hoos u dhigi karaan qiimaha si aad u bixiso qiyaastii $ 12.
Imodium waa dawo OTC oo laga yaabo in aysan daboolin Medicare iyo qorshayaasha caymiska. Qorshayaasha qaarkood waxay ku dabooli karaan foomka guud warqad dhakhtar qoro. Way fiicantahay in la hubiyo qaaciddada qorshahaaga caymiska si loo hubiyo. Celceliska qiimaha loperamide waa qiyaastii $ 26. Qiimo dhimista SingleCare, waxaad ku heli kartaa kiniiniyada guud ee loperamide qiyaastii $ 14. Si aad uga faa'iideysato keydinta OTC, weli waa inaad heshaa a dhakhtar kuu qoro .
| Lomotil | Imodium | |
| Caadi ahaan caymiska ayaa daboolaya? | Maaha | Maaha |
| Caadi ahaan waxaa daboolaya Medicare? | Maaha | Maaha |
| Qiyaasta caadiga ah | 2.5 mg diphenoxylate / 0.025 mg atropine, tiro 30 kiniin ah | 2 mg, tiro 30 kiniin ah |
| Bixinta lacagta caadiga ah ee 'Medicare' | $ 0– $ 150 | $ 0– $ 99 |
| Qiimaha SingleCare | $ 12 | $ 14 |
Dhibaatooyinka guud ee Lomotil iyo Imodium
Dhibaatooyinka ay keento Lomotil waxaa ka mid ah lulmo, dawakhaad, iyo lallabbo. Marka loo barbardhigo Imodium, Lomotil waxaa laga yaabaa inuu yeesho waxyeelo badan oo CNS ah oo ay ku jiraan madax xanuun, degganaansho la'aan, iyo jahwareer.
Saameynta ugu caansan ee la xiriirta Imodium waa calool istaag . Waxyeellooyinka kale ee caadiga ah waxaa ka mid ah dawakhaad, lallabbo, iyo calool xanuun ama calool xanuun.
Qiyaaso badan, waxyeelooyinka halista ah ee Lomotil iyo Imodium waxaa ku jiri kara lulmo daran, dhalanteed, iyo caajis. Dhibaatooyinka halista ah sida neefsashada oo gaabisa (Niyad-jabka neefsashada) sidoo kale waxay ku dhici karaan qiyaaso sun ah.
| Lomotil | Imodium | |||
| Saamaynta Side | Ma khuseysaa? | Joogtaynta | Ma khuseysaa? | Joogtaynta |
| Calool fadhiga | Maaha | - | Haa | 5.3% |
| Dawakhaad | Haa | * lama soo sheegin | Haa | 1.4% |
| Lallabbo | Haa | * | Haa | 1.8% |
| Calool xanuun | Haa | * | Haa | 1.4% |
| Matagid | Haa | * | Haa | * |
| Af qalalan | Haa | * | Haa | * |
| Hurdo | Haa | * | Haa | * |
| Madax xanuun | Haa | * | Maaha | - |
| Degganaansho la'aan | Haa | * | Maaha | - |
| Jahwareer | Haa | * | Maaha | - |
Tani ma noqon karto liistada dhameystiran ee waxyeelooyinka xun ee dhici kara. Fadlan tixraac dhakhtarkaaga ama daryeel caafimaad si aad wax badan uga ogaato.
Xigasho: DailyMed ( Lomotil ),, DailyMed ( Imodium )
Isdhexgalka daroogada ee Lomotil iyo Imodium
Lomotil wuxuu la falgeli karaa daawooyinka sida monoamine oxidase inhibitors (MAOIs) iyo CNS depressants. Qaadashada MAOI, sida selegiline ama phenelzine, oo leh Lomotil waxay kordhin kartaa halista qalalaasaha dhiig karka, ama dhiig kar khatar leh. Khatarta waxyeelada xun sidoo kale waa la kordhin karaa inta la qaadanaayo daawooyinka niyadjabka CNS sida barbiturates, benzodiazepines, iyo murqaha nasteexo .
Si ka duwan Lomotil, Imodium si aad ah ayaa looga shaqeeyaa beerka iyadoo loo adeegsado enzymes sida CYP3A4 enzyme iyo CYP2C8 enzyme. Daawooyinka xakameynaya, ama xiraya, enzymes-kan ayaa kordhin kara heerarka Imodium dhiiga. Natiijo ahaan, wada qaadashada daawooyinkan waxay kordhin kartaa halista waxyeelada xun.
| Daroogada | Fasalka Daroogada | Lomotil | Imodium |
| Selegiline Phenelzine Isocarboxazid Tranylcypromine | Kahortagayaasha Monoamine oxidase (MAOIs) | Haa | Maaha |
| Phenobarbital Pentobarbital Alprazolam Lorazepam Trazodone Oxycodone | Niyad jabka CNS | Haa | Haa |
| Saquinavir Itraconazole | Ka hortagayaasha CYP3A4 | Maaha | Haa |
| Gemfibrozil | CYP2C8 xannibaadayaasha | Maaha | Haa |
| Quinidine Ritonavir | Xakameeyayaasha P-glycoprotein | Maaha | Haa |
Tani ma aha liistada dhameystiran ee isdhexgalka daroogada. Fadlan la tasho dhakhtarkaaga kahor intaadan qaadan daawooyinkan.
Digniinta Lomotil iyo Imodium
Lomotil looma isticmaali karo carruurta da'doodu ka yar tahay 6 sano jir sababtoo ah halista sii kordheysa ee neefsashada iyo niyadjabka CNS. Kuwa cagaarshowga xannibaadda leh ama xasaasiyadda loo yaqaan 'diphenoxylate' ama atropine sidoo kale waa inay iska ilaaliyaan isticmaalka Lomotil.
Imodium ayaa la sheegay inay sababto Torsades de Pointes , wadnaha oo istaaga, iyo geerida marka lagu qaato qiyaaso ka badan intii lagu taliyey. Waxaa lagugula talinayaa inaad qaadato kaliya qiyaasta ugu yar ee loo baahan yahay sida uu ku faray bixiyahaaga daryeelka caafimaadka. Imodium waa in aan loo isticmaalin socod baradka iyo dhallaanka ka yar 2 sano jir sababo la xiriira halista neefsashada iyo murugada CNS.
Lomotil iyo Imodium waa in aan loo isticmaalin in lagu daaweeyo shubanka ay keento infekshannada bakteeriyada. Daawooyinkan looma isticmaali karo in lagu daaweeyo shubanka ay sababaan noolaha sida Clostridium adag iyo Salmonella .
La tasho dhakhtarkaaga haddii aad qabtid wax xaalad caafimaad ah kahor intaadan qaadan daawooyinkan. Waxaa lagugula talinayaa inaad ku qaadato daawooyinkan talobixin caafimaad bixiyahaaga daryeelka caafimaadka.
Su'aalaha badanaa la isweydiiyo ee ku saabsan Lomotil iyo Imodium
Waa maxay Lomotil?
Lomotil waa dawo dhakhtar qoro oo loo isticmaalo daweynta la socota ee shubanka. Lomotil waxaa lagu heli karaa nooc magac ah iyo noocyo guud. Waxaa loo qaadan karaa shuban ba'an ama dabadheeraad ah oo ku dhaca dadka waaweyn iyo carruurta da'doodu tahay 13 iyo wixii ka weyn.
Waa maxay Imodium?
Imodium waa daawada miiska laga soo iibsado (OTC) oo FDA loo oggol yahay in lagu daaweeyo shubanka. Imodium waxaa caadi ahaan loo isticmaalaa in lagu daaweeyo shuban-biyoodka socotada ah in kasta oo ay sidoo kale daaweyn karto shuban-biyoodka joogtada ah ee uu sababo IBS. Imodium waxay daaweyn kartaa dadka waaweyn iyo carruurta da'doodu tahay 2 sano iyo wixii ka weyn.
Lomotil iyo Imodium ma isku mid baa?
Maya. Lomotil iyo Imodium isku mid ma aha. In kasta oo ay u shaqeeyaan siyaabo isku mid ah, Lomotil waxaa lagu heli karaa oo keliya warqad dhakhtar qoro. Imodium waxaa laga iibsan karaa miiska lagu iibiyo.
Lomotil ama Imodium ma ka fiican yahay?
Lomotil iyo Imodium labaduba waa daawooyin waxtar leh oo lagu daaweeyo shubanka. Qaar cilmi baaris ayaa muujisay in uusan jirin farqi weyn oo u dhexeeya waxtarka labada. Si kastaba ha noqotee, kale waxbarashada waxay muujiyeen in Imodium uu ka waxtar badan yahay uguna dulqaadasho fiican yahay. Kala tasho dhakhtarkaaga xulashada daaweynta ugu fiican ee adiga kugu habboon.
Ma isticmaali karaa Lomotil ama Imodium inta aan uurka leeyahay?
Dhakhaatiirta qaar ayaa ogolaan kara isticmaalka Lomotil ama Imodium inta lagu guda jiro uurka kaliya haddii ay lagama maarmaan tahay. Haddii kale, Lomotil iyo Imodium guud ahaan laguma talin inta lagu jiro uurka sababo la xiriira suurtagalnimada waxyeellada uurjiifka. Kala hadal dhakhtarkaaga xulashooyinka shubanka inta aad uurka leedahay.
Ma ku isticmaali karaa Lomotil ama Imodium aalkolo?
Laguguma talin inaad cabto aalkolo inta aad isticmaaleysid Lomotil ama Imodium. Lomotil iyo Imodium waxay sababi karaan waxyeelo xun sida lulmo iyo dawakhaad. Cabitaanka khamrigu wuxuu kordhin karaa waxyeeladaan.
Maxaa Lomotil loo mamnuucay?
Lomotil ma aha daroogo mamnuuc ah. Si kastaba ha noqotee, waa Jadwalka V walaxda la xakameeyo sida ay u kala saartay DEA. Tani waxay ka dhigan tahay inay jirto suurtagalnimada ku takrifal iyo xadgudub markaad isticmaaleyso daroogada. Iskeed, diphenoxylate, maaddada ugu weyn ee firfircoon ee Lomotil, waa walaxda Jadwalka II oo leh awood sare oo xadgudub ah.
Miyaad qaadan kartaa Lomotil muddo dheer?
Lomotil laguma talinayo in loo isticmaalo in ka badan 10 maalmood cudurka shuban biyoodka. Xaaladaha qaarkood, Lomotil waxaa loo isticmaali karaa isticmaalka muddada-dheer, gaar ahaan shuban-biyoodka joogtada ah. Isticmaalka muddada-dheer ee Lomotil waa inuu kormeeraa dhakhtar.
Maxaa dhacaya haddii Imodium uusan joojin shubanka?
Imodium waa inay yareeyaan astaamaha shuban-yarta 48 saac gudahood. Haddii aad isku aragto mid ka mid ah kuwan soo socda, waa inaad isla markiiba wacdaa dhakhtarkaaga:
- Saxarada oo dhiig ka yimaado
- Qandho ama heerkul ka sarreeya 101.3 ° F
- Xanuun daran oo caloosha ah
- Gudbaya lix ama in ka badan saxaro dabacsan maalintii
- Shuban muddo ka badan 48 saacadood soconaya
- Astaamaha sida madax-xanuun daran, wareer, xabad xanuun, ama xanuun
