Trintellix iyo Lexapro: Kala duwanaanshaha, isku ekaanshaha, iyo yaa adiga kuu fiican
Daroogada Vs. SaaxiibDulmarka daroogada & kala duwanaanshaha ugu weyn | Xaaladaha la daweeyay | Wax ku oolnimada | Caymiska caymiska iyo isbarbardhiga qiimaha | Dhibaatooyinka ay keento | Isdhexgalka daroogada | Digniinta | Su'aalaha
In kabadan 16 milyan oo qaangaar ah oo Mareykan ah ayaa leh niyad jab (cillad weyn oo niyadjab leh), ku dhowaad 7 milyan oo qaangaar ahna waxay leeyihiin cillad guud oo walaac ah. Dhacdooyinkii ugu dambeeyay sida aafada COVID-19, waxay ahaayeen a isha walaaca dad badan.
Trintellix (vortioxetine) iyo Lexapro (escitalopram) waa laba daawo oo dhakhtar qoro oo loo isticmaalo niyad-jabka. Lexapro sidoo kale waxaa loo isticmaalaa walaaca. Labada daawoba waxaa ansaxiyay Maamulka Cuntada iyo Dawooyinka ee Mareykanka (FDA).
Trintellix iyo Lexapro waa qeyb ka mid ah koox daawooyin ah oo loo yaqaan 'SSRIs' (serotonin reuptake inhibitors) xulasho leh. SSRIs waxay ku shaqeeyaan iyagoo kordhiya heerarka serotonin ee maskaxda, taas oo ka caawisa hagaajinta calaamadaha niyadjabka. In kasta oo Trintellix iyo Lexapro ay labaduba yihiin SSRIs, haddana waxay leeyihiin xoogaa kala duwanaan ah, oo aan hoos ku tilmaami doonno.
Maxay yihiin farqiga ugu weyn ee u dhexeeya Trintellix iyo Lexapro?
Trintellix (vortioxetine) waa dawo SSRI ah. Waxaa lagu heli karaa oo keliya magaca magaca, qaab kiniin ah. Waxaa loo isticmaali karaa dadka waaweyn oo keliya. Laguma baran carruurta. Trintellix asal ahaan waxaa loo yaqaan Brintellix, laakiin kan magacaa la badalay si looga fogaado jahwareerka daawada antiplatelet ee loo yaqaan Brilinta.
Lexapro (escitalopram) waa SSRI. Lexapro waxaa lagu heli karaa labadaba nooc iyo qaab guud iyo sida kaniiniga ama xalka afka. Lexapro waxaa loo isticmaalaa dadka qaangaarka ah iyo dhalinyarada 12 sano iyo ka weyn ee niyadjabka, ama dadka waaweyn 18 sano iyo wixii ka weyn walaaca.
| Farqiga ugu weyn ee u dhexeeya Trintellix iyo Lexapro | ||
|---|---|---|
| Trintellix | Lexapro | |
| Fasalka daroogada | SSRI (xulashada serotonin reuptake inhibitor) | SSRI (xulashada serotonin reuptake inhibitor) |
| Summad / astaan guud | Summad | Nooc iyo astaan guud |
| Waa maxay magaca guud? | Vortioxetine | Escitalopram |
| Waa noocee (yada) daroogadu soo gasho? | Kiniin | Kiniin, xal |
| Waa maxay qiyaasta caadiga ah? | Ka bilow 10 mg maalintii ka dibna u kordhi 20 mg maalintii haddii loo dulqaato | 5 mg, 10 mg, ama 20 mg hal mar maalintii |
| Muddo intee le'eg ayaa daaweynta caadiga ah? | Kaladuwan | Kaladuwan |
| Ayaa si caadi ah u isticmaala daawada? | Dadka waaweyn | Dadka waaweyn iyo dhalinyarada (12 sano jir iyo ka weyn) |
Ma dooneysaa qiimaha ugu fiican Trintellix?
Isu qor digniinta qiimaha Trintellix oo ogow marka sicirka isbeddelo!
Hel digniinta qiimaha
Xaaladaha ay daweeyaan Trintellix iyo Lexapro
Trintellix waxaa lagu muujiyey in lagu daaweeyo cudurka weyn ee niyadjabka (MDD). Waxaa mararka qaarkood loo isticmaalaa off-sumadda cilada guud ee walwalka.
Lexapro waxaa lagu muujiyey in lagu daaweeyo MDD dadka qaangaarka ah iyo dhalinyarada da'doodu tahay 12-17 sano. Lexapro waxaa sidoo kale lagu muujiyey daaweynta guud ahaan khalkhalka walaaca dadka waaweyn.
| Xaaladda | Trintellix | Lexapro |
| Cudurka weyn ee niyadjabka (MDD) | Haa | Haa |
| Cilad-werwer guud | Off-calaamadda | Haa |
Trintellix ama Lexapro waxtar badan ma leedahay?
KU falanqaynta meta (falanqeyn daraasado badan) oo lagu daabacay 2018 ayaa lagu qiimeeyay 21 antidepressant. Labadaba Trintellix iyo Lexapro ayaa la ogaaday inay ka waxtar badan yihiin daawooyinka kale ee diiqadda lagu buufiyo. Labadooduba way ka fiicnaayeen dulqaadlayaasha kale ee dawooyinka lidka ku ah sidoo kale.
KU barasho oo ay samaysay shirkadda soo saarta Trintellix waxay ku soo gabagabeysay in Trintellix iyo Lexapro ay labaduba yihiin daawooyin niyadjabka wax ku ool ah. Daraasadda ayaa sidoo kale soo warisay in Trintellix uu leeyahay dhacdooyin badan oo ka mid ah waxyeelooyinka qaarkood, sida lallabbo iyo cuncun ka badan Lexapro.
Bixiyahaaga daryeelka caafimaad ayaa kuu go'aamin kara daawada kuugu waxtar badan adiga oo tixgelinaya xaaladahaaga caafimaad iyo taariikhdaada iyo waliba daawooyinka aad qaadato ee la falgeli kara Trintellix ama Lexapro.
Ma dooneysaa qiimaha ugu fiican Lexapro?
Saxiix digniinta qiimaha Lexapro oo ogow goorta sicirka isbeddelo!
Hel digniinta qiimaha
Daboolida iyo qiimaha isbarbar dhiga Trintellix iyo Lexapro
Trintellix waxaa daboolaya caymiska badankood iyo qorshayaasha Medicare Qaybta D. Si kastaba ha noqotee, waxaa ugu wanaagsan in laga hubiyo qorshahaaga faahfaahinta caymiska gaarka ah. Trintellix waxaa kaliya lagu heli karaa magaca sumadda. Waxay ku kici kartaa wax ka badan $ 500 # 30, kiniiniyada 20 mg. Waxaad ku isticmaali kartaa kuuboon SingleCare bilaash ah si aad u yareyso qiimaha ugu yaraan $ 350.
Lexapro badanaa waxaa daboola caymiska iyo Medicare Qaybta D. Nooca guud wuxuu badanaa leeyahay lacag bixin yar. Badeecada magaca ku caan baxday badanaa waxay leedahay lacag bixin aad u sareysa ama waxaa laga yaabaa inaanay daboolin haba yaraatee. Generic Lexapro wuxuu ku kacayaa $ 70 # 30, 10 mg kiniin guud. Kaarka SingleCare wuxuu hoos u dhigi karaa qiimaha guud ilaa $ 8.
| Trintellix | Lexapro | |
| Caadi ahaan caymiska ayaa daboolaya? | Haa | Haa (guud) |
| Caadi ahaan waxaa daboola Medicare Qaybta D? | Haa | Haa (guud) |
| Qiyaasta caadiga ah | 30, kiniiniyada 20 mg | 30, kiniiniyada 10 mg |
| Bixinta lacagta caadiga ah ee 'Medicare' | $ 3- $ 14 | $ 0- $ 30 |
| Qiimaha SingleCare | $ 352- $ 365 | $ 8- $ 40 |
Soo qaado kaarka dhimista farmasiga
Dhibaatooyinka guud ee Trintellix iyo Lexapro
Saamaynta ugu badan ee Trintellix waa lallabbo, oo badanaa khafiif ah ama dhexdhexaad ah waxayna socotaa illaa laba toddobaad. Dhacdooyinka kale ee foosha xun waxaa ka mid ah waxyeelo xagga galmada ah, lallabbo, calool istaag, matag, shuban, afka oo qallalan, iyo dawakhaad.
Dhibaatooyinka ugu badan ee Lexapro waa madax xanuun, lallabbo, dhibaatooyinka galmada, lulmo, iyo hurdo la'aan.
Qoraal kasta oo cusub ama dib loo soo buuxiyay oo ah Trintellix ama Lexapro, waxaad ku heli doontaa hage daawo ah oo ka hadlaya waxyeelooyinka, digniinta, iyo macluumaadka kale ee muhiimka ah.
Tani ma aha liistada buuxda ee waxyeellooyinka. Dhibaatooyinka kale ee xun ayaa dhici kara. La tasho daryeel caafimaad bixiyahaaga si aad u hesho liis buuxa oo ah waxyeelooyin suurtagal ah.
| Trintellix * | Lexapro | |||
| Waxyeellada | Ma khuseysaa? | Joogtaynta | Ma khuseysaa? | Joogtaynta |
| Madax xanuun | Haa | % lama sheegin | Haa | 24% |
| Lallabbo | Haa | 21-32% | Haa | 18% |
| Cudurka Ejaculation / cilladda galmada | Haa | 16-34% | Haa | 14% |
| Shuban | Haa | 7-10% | Haa | 8% |
| Calool fadhiga | Haa | 3-6% | Haa | 3% |
| Af qalalan | Haa | 6-8% | Haa | 9% |
| Hurdo | Maaha | - | Haa | 13% |
| Dawakhaad | Haa | 6-9% | Haa | 5% |
| Hurdo la'aan | Maaha | - | Haa | 12% |
* waxyeelooyinka waxay kuxirantahay qiyaasta
Xigasho: DailyMed ( Trintellix ),, DailyMed ( Lexapro )
Isdhexgalka daroogada ee Trintellix iyo Lexapro
Sababtoo ah labada daroogo waa isku nooc, waxay leeyihiin isdhexgal daroogo oo isku mid ah.
MAOI (monoamine oxidase inhibitors) waxay la falgalaan Trintellix iyo Lexapro. Isticmaalkooda waa in lakala saaraa 14-21 maalmood, iyadoo kuxiran qorshaha daaweynta shaqsiyeed. Isku darka MAOI ee leh Trintellix ama Lexapro ayaa kordhin kara halista ah cilladda serotonin , xaalad degdeg ah oo caafimaad oo nafta halis gelisa sababtoo ah soo dhiska serotonin.
Triptans-ka waxaa loo isticmaali jiray in lagu daaweeyo dhanjafka, sida Imitrex (sumatriptan), iyo daawooyinka kale ee niyadjabka, sida Elavil ama Cymbalta, looma isticmaali karo iskudarka Trintellix ama Lexapro khatarta serotonin syndrome. Sidoo kale, qufaca joojiya dextromethorphan-oo laga helo Robitussin-DM iyo sidoo kale qufac iyo waxyaabo badan oo qabow-waa in laga fogaadaa maadaama ay sidoo kale sababi karto serotonin syndrome markii lagu daro Trintellix ama Lexapro.
Daawooyinka kale ee laga yaabo inay la falgalaan Trintellix ama Lexapro waxaa ka mid ah daawooyinka non-steroidal anti-inflammatory drugs (NSAIDs), sida aspirin ama ibuprofen, iyo daawooyinka xinjirowga lidka ku ah (dhiig khafiifiyeyaasha), sida warfarin. Iska ilaali aalkolada markaad qaadaneyso Trintellix ama Lexapro.
Tani ma aha liistada buuxa ee isdhexgalka daroogada. La tasho daryeel caafimaad bixiyahaaga si aad u hesho liistada dhameystiran ee isdhexgalka daroogada.
| Daroogada | Fasalka daroogada | Trintellix | Lexapro |
| Phenelzine Rasagiline Selegiline Tranylcypromine | MAOIs | Haa | Haa |
| Khamriga | Khamriga | Haa | Haa |
| Rizatriptan Sumatriptan Zolmitriptan | Tripans | Haa | Haa |
| John's Wort | Kordhin | Haa | Haa |
| Warfarin | Anticoagulant | Haa | Haa |
| Codein Hydrocodone Morphine Oxycodone Tramadol | Opioids | Haa | Haa |
| Dextromethorphan (qufac badan iyo alaab qabow) | Xakamaynta qufaca | Haa | Haa |
| Azithromycin Clarithromycin Erythromycin | Antibiyootikada loo yaqaan 'Macrolide antibiotics' | Maaha | Haa |
| Aspirin Ibuprofen Meloxicam Nabumetone Naproxen | NSAIDs | Haa | Haa |
| Desvenlafaxine Duloxetine Venlafaxine | Daawooyinka murugada ee SNRI | Haa | Haa |
| Amitriptyline Desipramine Imipramine Nortriptyline | Dawooyinka lidka ku ah diiqadaha ee loo yaqaan 'Tricyclic antidepressants' | Haa | Haa |
| Alprazolam Clonazepam Diazepam | Benzodiazepines | Maaha | Haa |
Digniinta Trintellix iyo Lexapro
Dhammaan SSRIs, oo ay ku jiraan Trintellix iyo Lexapro, waxay leeyihiin digniin sanduuq ah oo ku saabsan is-dilka. Caruurta, dhalinyarada, iyo dhalinyarada (ilaa 24 sano jir) ee qaata dawooyinka lidka diiqadda waxay leeyihiin halista sii kordheysa ee fikradaha isdilka iyo dhaqanka. Dhammaan bukaan socodka dawooyinka lidka diiqadda waa in si taxaddar leh loola socdaa.
Digniinta kale waxaa ka mid ah:
- Cudurka 'Serotonin syndrome' waa mid halis ah, xaalad deg-deg ah oo nafta halis gelisa oo ay keento soo-saarista serotonin aad u tiro badan. Bukaannada qaata Trintellix ama Lexapro waa in si taxaddar leh loola socdaa calaamadaha iyo astaamaha serotonin syndrome sida dhalanteedka, suuxdinta, isbeddelka cadaadiska dhiigga, iyo kacdoonka. Bukaanku waa inay raadsadaan daaweyn caafimaad oo deg-deg ah haddii mid ka mid ah astaamahan ay dhacaan. Bukaannada qaata daawooyinka kale ee kordhiya heerarka serotonin (triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, dextromethorphan, amphetamines, St. John’s Wort, iyo MAOIs) ayaa halista ugu badan ugu jira serotonin syndrome.
- SSRIs waxay kordhin kartaa halista dhiigbaxa. Khatartu waxay sii kordheysaa isticmaalka asbiriinka, NSAIDs, ama warfarin.
- Dhaqdhaqaaqa mania ama hypomania ayaa dhici kara. Bukaannada qaba laba-cirifoodka, daawada lidka diiqadda waxay soo dadajin kartaa dhacdo isku dhafan / manic ah.
- Ka fogow SSRIs ama u isticmaal taxaddar bukaanada leh xaglo cidhiidhi ah oo jidh ahaaneed oo aan la daweyn (glaucoma angle-closure). Trintellix iyo Lexapro waxay sababi karaan dhibaatooyin xagga aragga ah sida isha oo xanuun, isbeddel aragga, casaan, iyo barar. Weydii daryeel caafimaad bixiyahaaga haddii aad khatar ku jirto.
- Hyponatremia (heerarka soodhiyamka hooseeya) oo ay ugu wacan tahay cilladda dheecaanka hoormoonka antidiuretic ee aan habboonayn (SIADH) ayaa dhici kara. Bukaanku waxay la kulmi karaan madax xanuun, feejignaan la'aan, xusuusta oo xumaata, jahwareer, daciifnimo, iyo degganaansho la'aan, taasoo u horseedi karta dhicitaan. Kiisas aad u daran ayaa dhici kara. Bukaanku waa inay raadsadaan daaweyn degdeg ah haddii astaamuhu dhacaan, oo ay joojiyaan SSRI.
- Markaad joojineyso Lexapro, astaamaha ka bixitaanka sida kacsiga ayaa dhici kara. Bukaanku waa inay daroogada si tartiib tartiib ah u joojiyaan oo aysan marna si lama filaan ah u joojin.
- Trintellix si lama filaan ah ayaa loo dhejin karaa haddii loo baahdo, laakiin soo-saaraha ayaa kugula talinaya wax yar oo duub ah si looga fogaado astaamaha sida madax-xanuun iyo murqaha murqaha. Bixiyahaaga daryeelka caafimaad ayaa kaala talin kara sida ugu wanaagsan ee loo joojin karo Trintellix ama Lexapro.
- Ha kaxeyn baabuur ama ha ku shaqeynin mishiin ilaa aad ka ogaato sida ay kuu saameyso Trintellix ama Lexapro.
- Kala hadal daryeel caafimaad bixiyahaaga isticmaalka Trintellix ama Lexapro haddii aad leedahay taariikh suuxdin.
- Marar dhif ah, waxaa jiray warbixino ficil celin iyo xasaasiyad xasaasiyadeed / fal-celin anaphylaxis oo nidaamsan oo dhimasho keenay. Haddii aad isku aragto furuuruc ama astaamo xasaasiyadeed, jooji qaadashada Trintellix ama Lexapro isla markaana raadso daaweyn dhakhso leh.
- Lexapro wuxuu sababi karaa QT kordhinta iyo xuubka wadnaha. Bukaannada qaarkood waxay ku jiraan halis sare xaalad caafimaad ama daawooyin kale awgood. Weydii bixiyaha xanaanada caafimaadkaaga hadii Lexapro adiga amaan kuu yahay.
- U isticmaal Lexapro taxaddar bukaanka qaba dhibaatooyinka kalyaha.
Trintellix ama Lexapro waa in loo isticmaalaa uurka kaliya haddii waxtarka hooyadu ka weyn yahay halista ilmaha. Joojinta daawada waxay sababi kartaa soo noqnoqasho niyad jab ama walaac. Sidaa darteed, bukaan-socodka waa in loo qiimeeyaa xaalad-xaalad-xaalad ah. Bixiyahaaga daryeelka caafimaad wuxuu miisaami karaa halista iyo faa'iidooyinka isticmaalka SSRI muddada uurka. Neonates-ka ay soo gaadhay SSRIs saddexda bilood ee saddexaad waxay soo saareen dhibaatooyin u baahan isbitaal dhigis daba dheeraada, kaalmada neefta, iyo quudinta tubada. Haddii aad horey ugu jirtay Trintellix ama Lexapro oo aad ogaato inaad uur leedahay, la xiriir dhaqtarkaaga isla markiiba.
Su'aalaha badanaa la isweydiiyo ee ku saabsan Trintellix iyo Lexapro
Waa maxay Trintellix?
Trintellix waa SSRI, ama xulashada serotonin reuptake inhibitor. Waxaa lagu heli karaa foomka magaca oo loo isticmaalaa in lagu daaweeyo niyad-jabka dadka waaweyn.
Waa maxay Lexapro?
Lexapro waa SSRI. Lexapro waxay daweyn kartaa niyad-jabka iyo walwalka. Waxaa lagu heli karaa nooc iyo nooc labadaba (escitalopram).
Trintellix iyo Lexapro ma isku mid baa?
Trintellix iyo Lexapro labaduba waxay ku jiraan qaybta SSRI ee dawooyinka dhakhtarku qoro. Waxay la mid yihiin, laakiin isku mid ma aha. Waxay leeyihiin xoogaa khilaaf ah, sida kor lagu soo sheegay. Daawooyinka kale ee SSRI ee laga yaabo inaad maqashay waxaa ka mid ah Celexa (citalopram), Luvox (fluvoxamine), Paxil (paroxetine), Prozac (fluoxetine), iyo Zoloft (sertraline).
Nooc kale oo daroogo ah oo laga yaabo inaad maqashay waa nooca SNRI ee daroogada, oo ay ku jiraan Cymbalta (duloxetine), Effexor (venlafaxine), iyo Pristiq (desvenlafaxine).
Ma Trintellix mise Lexapro ayaa ka fiican?
Eeg qaybta kore ee waxtarka — waxaa jira xog aad uyar oo isbarbar dhigaysa Trintellix iyo Lexapro. Daraasaduhu waxay muujinayaan in labada daroogo ay waxtar leeyihiin oo si la mid ah loo dulqaatay, in kastoo labada daawooyinba ay leeyihiin waxyeelo dadka qaar dhib ku noqon kara, sida lallabbo ama waxyeelo dhanka galmada ah.
Bixiyahaaga daryeelka caafimaad ayaa go'aamin kara daawada adiga kuufiican, adoo tixgelinaya duruufahaaga gaarka ah. Tusaale ahaan, haddii qiimuhu yahay qodob go'aaminaya, guud ahaan guud ahaan 'Lexapro' ayaa laga yaabaa inay ka qiimo jaban tahay, waxaadna u dhowdahay inaad raacdo nidaamka. Ama, haddii waxyeelada galmada ay tahay wax laga walwalo, waxaad ku sii fiicnaan kartaa Trintellix, oo laga yaabo inay yeelato saameyn yar oo galmo ah.
Ma isticmaali karaa Trintellix ama Lexapro inta aan uurka leeyahay?
La tasho daryeel caafimaad bixiyahaaga wixii talo ah. Isaga ama iyada ayaa miisaami doona faa'iidooyinka qaadashada dawada lidka diiqadda iyo halista ku jirta ilmaha. Neonates-ka loo soo bandhigay daawooyinka niyadjabka qaarkood, oo ay ku jiraan SSRIs, saddexda bilood ee saddexaad ee uurka, waxay yeesheen dhibaatooyin.
Haddii aad horey ugu jirtay Trintellix ama Lexapro oo aad ogaato inaad uur leedahay, la tasho dhakhtarkaaga OB-GYN isla markiiba wixii talo ah. Hadaad tahay naas nuujinta , la tasho OB-GYN sidoo kale.
Ma ku isticmaali karaa Trintellix ama Lexapro aalkolo?
Maya. Trintellix ama Lexapro waa in aan lagu qaadin aalkolo maxaa yeelay isku dhafka ayaa kordhin kara halista niyad-jabka neefsashada (neefsashada oo gaabisa, helitaanka oksijiin ku filan) iyo kordhinta suuxinta iyo lulmada, iyo wiiqidda feejignaanta. Isku darka ayaa sidoo kale sii xumeyn kara walaaca iyo niyadjabka.
Muxuu Trintellix uga duwan yahay dawooyinka lidka diiqadaha kale?
Trintellix wuxuu u shaqeeyaa sida antagonist, agonist, iyo qayb ka mid ah agonist of receptors badan oo serotonin si loo caawiyo calaamadaha niyadjabka. Daawooyinka kale ee ku jira fasalka SSRI, sida Lexapro, waxay ku shaqeeyaan kordhinta dhaqdhaqaaqa serotonin ee habka dhexe ee neerfaha.
Trintellix miyuu keenaa miisaanka oo kordha?
Caafimaad waxbarashada muujisay in Trintellix uusan saameyn ku yeelan miisaanka. Ma jirin farqi u dhexeeya isbeddelada miisaanka ee u dhexeeya dadka qaatay Trintellix iyo dadka qaatay placebo (kiniin aan firfircooneyn). Macluumaadka ka dambeeya suuq-geynta ayaa sheegaya miisaanka oo kordha laakiin ma sheegayo boqolkiiba dadka la kulmay kororka miisaanka. La tasho xirfadlahaaga daryeelka caafimaadka haddii miisaankaagu kordho walaac.
