Lovastatin vs Atorvastatin: Farqiga udhaxeeya iyo isku ekaanshaha

Daroogada Vs. Saaxiib

Lovastatin iyo atorvastatin waa dawooyin isdabajoog ah oo daaweyn kara kolestaroolka sare. Labada daaweynba waxaa lagu sifeeyay inay yihiin HMG-coA reductase inhibitors. Waxay asal ahaan ka shaqeeyaan iyagoo si aan toos ahayn u xannibaya soo-saarka kolestaroolka dhiiga ku jira. Iyagoo hoos u dhigaya kolestaroolka LDL, waxay kaa caawin karaan kahortaga halista wadno qabadka iyo istaroogga kuwa qaba cudurka wadnaha. In kasta oo ay iskaga mid yihiin, haddana waxay kaloo leeyihiin xoogaa khilaaf ah oo laga wada hadli doono.

Lovastatin

Lovastatin waa magaca guud ee Mevacor iyo Altoprev. Waxaa loo qoraa in lagu daaweeyo halbowlayaasha wadnaha iyo hypercholesterolemia (kolestarool sare). Kuwa qaba cudurrada wadnaha iyo xididdada dhiigga ayaa sidoo kale lagu daaweyn karaa lovastatin si loo yareeyo wadarta guud ee kalastaroolka iyo heerarka LDL.

Lovastatin waxaa loo heli karaa 10 mg, 20 mg, iyo 40 mg kiniin afka ah. Altoprev waa magaca nooca nooca la sii dheereeyey ee la heli karo oo ah 20 mg, 40 mg, ama 60 mg kiniin afka ah. Lovastatin waxaa lagula talinayaa in lagu qaato cuntada fiidkii ah. Tani waxay sabab u tahay kordhinta nuugista lovastatin ee qaadashada cuntada. Kuwa qaba dhibaatooyinka kalyaha waxay ubaahan karaan inay qaataan qadar yar si looga hortago halista waxyeelada.

Atorvastatin

Atorvastatin waa magaca guud ee Lipitor. Waxaa loo isticmaalaa in lagu yareeyo wadarta kolestaroolka iyo LDL kolestaroolka shaqsiyaadka leh heerar dhiig oo sarreeya. Waxaa sidoo kale loo qoraa si loo yareeyo halista dhimashada wadnaha iyo istaroogga.

Atorvastatin waxaa loo qaataa kiniin afka ah oo ku jira xoogaga 10 mg, 20 mg, 40 mg, ama 80 mg. Si ka duwan lovastatin, waa la qaadan karaa wakhti kasta oo maalintii ah. Tani waxay ugu wacan tahay nus nus nololeedkeeda. Si kastaba ha noqotee, laguma talinayo in lala qaato cuntada. Atorvastatin sidoo kale laguma talinayo kuwa qaba cudurka beerka ee daran.

Lovastatin vs Atorvastatin Side by Isbarbardhiga Side

Lovastatin iyo atorvastatin waa laba dawo oo statin ah oo leh egyihiin badan. In kasta oo ay siyaabo kala duwan isugu egyihiin, haddana waxay leeyihiin kala duwanaansho muhiim ah. Labada daawoba hoosta ayaa dib loogu eegi karaa.

Lovastatin	Atorvastatin
Loo Qoray
Kalastaroolka sareeya Triglycerides Sare Ka Hortagga Cudurka Wadnaha iyo dhacdooyinka la xiriira Wadnaha halbowlaha wadnaha Cudurka wadnaha ee daran Cudurka 'Atrial fibrillation'	Kalastaroolka sareeya Triglycerides Sare Ka Hortagga Cudurka Wadnaha iyo dhacdooyinka la xiriira Hyperlipoproteinemia Cudurka xididdada dhiigga
Qoondaynta Daroogada
HMG CoA reductase joojiyeyaasha	HMG CoA reductase joojiyeyaasha
Soo saare
Guud	Guud
Saameynada Caadiga ah
Calool xanuun Calool fadhiga Xanuun wadajir ah Madax xanuun Murqo xanuun	Nasopharyngitis Murqo xanuun Xanuun wadajir ah Shuban Caabuqa kaadi mareenka Calool xanuun Xanuun xagjir ah
Ma jiraa wax guud?
Lovastatin waa magaca guud.	Atorvastatin waa magaca guud.
Caymis ma ku jiraa?
Waxay ku kala duwan yihiin hadba sida adeeg bixiyahaagu leeyahay	Waxay ku kala duwan yihiin hadba sida adeeg bixiyahaagu leeyahay
Foomamka Qiyaasta
Kiniin afka ah	Kiniin afka ah
Celceliska Qiimaha Lacagta
30 (halkii kaniiniyada 30)	519 (halkii kaniini 30)
Qiima dhimista SingleCare
Qiimaha Lovastatin	Qiimaha Atorvastatin
Isdhexgalka Daroogada
CYP3A4 inhibitors (ketoconazole, itraconazole, posaconazole, voriconazole, erythromycin, clarithromycin, HIV protease inhibitors, telaprevir, nefazodone, boceprevir, iwm) Cyclosporine Kahortagayaasha 'Protease inhibitors' (tipranavir, ritonavir, saquinavir, fosamprenavir, nelfinavir) Amiodarone Colchicine Ranolazine Fenofibrate Gemfibrozil Niacin Diltiazem Danazol Dronedarone Verapamil Casiirka canabka	CYP3A4 inhibitors (ketoconazole, itraconazole, posaconazole, voriconazole, erythromycin, clarithromycin, HIV protease inhibitors, telaprevir, nefazodone, boceprevir, iwm) Cyclosporine Kahortagayaasha 'Protease inhibitors' (tipranavir, ritonavir, saquinavir, fosamprenavir, nelfinavir) Fenofibrate Gemfibrozil Niacin Digoxin Diltiazem Ka hortagga afka Rifampin Casiirka canabka
Ma isticmaali karaa inta aan qorsheynayo uurka, uurka, ama naasnuujinta?
Lovastatin wuxuu ku jiraa Uurka Nooca X waxaana laga yaabaa inuu sababo waxyeelo uurjiifka ah markii la siiyo haweenka uurka leh. Lovastatin laguma talinayo haweenka uurka leh.	Atorvastatin wuxuu ku jiraa Uurka Nooca X waxaana laga yaabaa inuu sababo waxyeelo uurjiifka ah markii la siiyo haweenka uurka leh. Atorvastatin laguma talinayo haweenka uurka leh.

Soo Koobid

Lovastatin iyo atorvastatin waa daawooyin statin waxtar u leh yareynta kolestaroolka. Labadaba waxaa loo isticmaalaa in looga hortago dhibaatooyinka wadnaha sida wadno istaagga iyo istaroogga bukaannada qaarkood. In kasta oo labada daawooyinba ay u shaqeeyaan siyaabo isku mid ah, haddana waxay kaloo ku kala duwan yihiin sida loo isticmaalo.

Dhanka awooda, daraasaduhu waxay muujiyeen in atorvastatin uu ka awood badan yahay lovastatin. Kuwa qaata atorvastatin waxaa lagu ogaadey inay hoos u dhac weyn kuyimaadeen kolestaroolka LDL. Si kastaba ha noqotee, labada daawoba waxay wax ku ool u yihiin yareynta halista dhacdooyinka la xiriira cudurka wadnaha.

Lovastatin waxaa badanaa lagula talinayaa in lagu qaato habeenkii iyadoo la cuno sababo la xiriira nolosheeda nuska yar. Dhinaca kale, atorvastatin waa la qaadan karaa subaxa hore ama habeenkii.

Labada daawoba waxaa lagu shiiday enzyme-ka CYP3A4 ee ku jira beerka. Sababtaas awgeed, waxay wadaagaan waxyeelo isku mid ah iyo isdhexgalka daroogada. Tusaale ahaan, looma isticmaali karo ka hortagayaasha xoog leh ee enzyme-ka taas oo kordhin karta halista waxyeellooyinka.

Isticmaalka lovastatin ama atorvastatin waa in lagala hadlaa takhtarkaaga. Labada daawo waa inaan loo isticmaalin inta lagu guda jiro uurka sababtoo ah halista la xaqiijiyay ee waxyeelada uurjiifka. Khatartooda waxyeellooyinka iyo isdhexgalka daroogooyinka badan dartiis, waxaa muhiim ah in si taxaddar leh dib loogu eego labadaba daawooyinka 'statin'.